Association of vitamin D metabolism gene polymorphisms with autoimmunity: evidence in population genetic studies

AI Ruiz-Ballesteros, MR Meza-Meza… - International journal of …, 2020 - mdpi.com
A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

Vitamin D and genetic susceptibility to multiple sclerosis

C Scazzone, L Agnello, G Bivona, B Lo Sasso… - Biochemical …, 2021 - Springer
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS), resulting from the interaction among genetic, epigenetic, and environmental factors …

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

A Ghaseminejad-Raeini, A Ghaderi, A Sharafi… - Frontiers in …, 2023 - frontiersin.org
For many years, vitamin D has been acknowledged for its role in maintaining calcium and
phosphate balance. However, in recent years, research has assessed its …

Ultraviolet radiation, vitamin D and multiple sclerosis

RM Lucas, SN Byrne, J Correale… - Neurodegenerative …, 2015 - Taylor & Francis
There is compelling epidemiological evidence that the risk of developing multiple sclerosis
is increased in association with low levels of sun exposure, possibly because this is …

[HTML][HTML] Molecular insights into the pathogenic impact of vitamin D deficiency in neurological disorders

MJ Anwar, SK Alenezi, AH Alhowail - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neurological disorders are the major cause of disability, leading to a decrease in quality of
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …

[HTML][HTML] A review of the critical role of vitamin D axis on the immune system

G Daryabor, N Gholijani, FR Kahmini - Experimental and Molecular …, 2023 - Elsevier
In recent years, the physiological and molecular functions of vitamin D (Vit-D) have been
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …

Association between vitamin D receptor (VDR) polymorphisms and the risk of multiple sclerosis (MS): an updated meta-analysis

D Imani, B Razi, M Motallebnezhad, R Rezaei - BMC neurology, 2019 - Springer
Background The association between the Vitamin D Receptor (VDR) gene polymorphism
and the risk of Multiple sclerosis (MS) has been evaluated in several researches. However …

The association of vitamin D receptor polymorphisms with multiple sclerosis in a case-control study from Kuwait

RA Al-Temaimi, A Al-Enezi, A Al-Serri, R Al-Roughani… - PloS one, 2015 - journals.plos.org
Vitamin D deficiency is associated with several diseases including multiple sclerosis (MS).
Several factors influence vitamin D levels and its optimal multi-function maintenance. Our …

Vitamin D receptor genetic polymorphisms and the risk of multiple sclerosis: A systematic review and meta-analysis

A Mohammadi, A Azarnezhad, H Khanbabaei… - Steroids, 2020 - Elsevier
There are conflicting results regarding the exact effect of the vitamin D receptor (VDR) gene
polymorphisms on the susceptibility to multiple sclerosis (MS). Therefore, we aimed to …

Predisposing role of vitamin D receptor (VDR) polymorphisms in the development of multiple sclerosis: A case-control study

R Abdollahzadeh, MS Fard, F Rahmani… - Journal of the …, 2016 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative
disease of the central nervous system (CNS) with a complex etiology. Given the Vitamin D …