Monotopic membrane proteins join the fold
Monotopic membrane proteins, classified by topology, are proteins that embed into a single
face of the membrane. These proteins are generally underrepresented in the Protein Data …
face of the membrane. These proteins are generally underrepresented in the Protein Data …
Functional innovation from changes in protein domains and their combinations
Highlights•An update of recent papers on functional innovations with domains.•Interplay
between changes in a domains function and its interactors/domain partners.•Comparative …
between changes in a domains function and its interactors/domain partners.•Comparative …
Mutations in transmembrane proteins: diseases, evolutionary insights, prediction and comparison with globular proteins
Membrane proteins are unique in that they interact with lipid bilayers, making them
indispensable for transporting molecules and relaying signals between and across cells …
indispensable for transporting molecules and relaying signals between and across cells …
Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA
N Vuksanovic, JR Clasman, B Imperiali… - Protein …, 2024 - Wiley Online Library
In selected Campylobacter species, the biosynthesis of N‐linked glycoconjugates via the pgl
pathway is essential for pathogenicity and survival. However, most of the membrane …
pathway is essential for pathogenicity and survival. However, most of the membrane …
The mARS complex: a critical mediator of immune regulation and homeostasis
SB Amanya, D Oyewole-Said, KJ Ernste… - Frontiers in …, 2024 - frontiersin.org
Over the course of evolution, many proteins have undergone adaptive structural changes to
meet the increasing homeostatic regulatory demands of multicellularity. Aminoacyl tRNA …
meet the increasing homeostatic regulatory demands of multicellularity. Aminoacyl tRNA …
Molecular insights of exercise therapy in disease prevention and treatment
Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the
prevention and treatment of various diseases, the underlying biological mechanisms have …
prevention and treatment of various diseases, the underlying biological mechanisms have …
Evolution and adaptation of single-pass transmembrane proteins
ID Pogozheva, AL Lomize - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
A comparative analysis of 6039 single-pass (bitopic) membrane proteins from six
evolutionarily distant organisms was performed based on data from the Membranome …
evolutionarily distant organisms was performed based on data from the Membranome …
Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans
The dramatic increase in membrane proteome complexity is arguably one of the most pivotal
evolutionary events that underpins the origin of multicellular animals. However, the origin of …
evolutionary events that underpins the origin of multicellular animals. However, the origin of …
The first identification of complete Eph-ephrin signalling in ctenophores and sponges reveals a role for neofunctionalization in the emergence of signalling domains
Background Animals have a greater diversity of signalling pathways than their unicellular
relatives, consistent with the evolution and expansion of these pathways occurring in …
relatives, consistent with the evolution and expansion of these pathways occurring in …
Dimensional crossover of acoustic phonon lifetime in -MoSe
P Soubelet, AA Reynoso, A Fainstein… - arXiv preprint arXiv …, 2018 - arxiv.org
A time-resolved observation of coherent interlayer longitudinal acoustic phonons in 2$ H $-
MoSe $ _2 $ is reported. A femtosecond pump-probe technique is used to investigate the …
MoSe $ _2 $ is reported. A femtosecond pump-probe technique is used to investigate the …