Current status of pesticide effects on environment, human health and it's eco-friendly management as bioremediation: A comprehensive review

VM Pathak, VK Verma, BS Rawat, B Kaur… - Frontiers in …, 2022 - frontiersin.org
Pesticides are either natural or chemically synthesized compounds that are used to control a
variety of pests. These chemical compounds are used in a variety of sectors like food …

The amyotrophic lateral sclerosis exposome: recent advances and future directions

SA Goutman, MG Savelieff, DG Jang, J Hur… - Nature Reviews …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration with
typical survival of only 2–5 years from diagnosis. The causes of ALS are multifactorial …

[HTML][HTML] Glyphosate disturbs various epigenetic processes in vitro and in vivo–a mini review

B Bukowska, E Woźniak, P Sicińska, K Mokra… - Science of The Total …, 2022 - Elsevier
Glyphosate in the concentrations corresponding to environmental or occupational exposure
has been shown to induce epigenetic changes potentially involved in carcinogenesis. This …

Linking prenatal environmental exposures to lifetime health with epigenome-wide association studies: state-of-the-science review and future recommendations

KM Bakulski, F Blostein, SJ London - Environmental health …, 2023 - ehp.niehs.nih.gov
Background: The prenatal environment influences lifetime health; epigenetic mechanisms
likely predominate. In 2016, the first international consortium paper on cigarette smoking …

The role of DNA methylation in personalized medicine for immune-related diseases

MK Gupta, H Peng, Y Li, CJ Xu - Pharmacology & Therapeutics, 2023 - Elsevier
Epigenetics functions as a bridge between host genetic & environmental factors, aiding in
human health and diseases. Many immune-related diseases, including infectious and …

Dynamic changes of DNA methylation induced by benzo (a) pyrene in cancer

H Wang, B Liu, H Chen, P Xu, H Xue, J Yuan - Genes and Environment, 2023 - Springer
Abstract Benzo (a) pyrene (BaP), the earliest and most significant carcinogen among
polycyclic aromatic hydrocarbons (PAHs), has been found in foods, tobacco smoke, and …

Associations of heavy metals with activities of daily living disability: an epigenome-wide view of DNA methylation and mediation analysis

L Xiao, H Cheng, H Cai, Y Wei, G Zan… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Exposure to heavy metals has been reported to be associated with multiple
diseases. However, direct associations and potential mechanisms of heavy metals with …

Pesticide use and risk of systemic autoimmune diseases in the Agricultural Health Study

CG Parks, KH Costenbader, S Long, JN Hofmann… - Environmental …, 2022 - Elsevier
Background Systemic lupus erythematosus (SLE) risk has been associated with pesticide
use, but evidence on specific pesticides or other agricultural exposures is lacking. We …

Association of glyphosate exposure with blood DNA methylation in a cross-sectional study of postmenopausal women

RM Lucia, WL Huang, KV Pathak… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Glyphosate is the most commonly used herbicide in the world and is purported
to have a variety of health effects, including endocrine disruption and an elevated risk of …

A Review of the Epigenetic Clock: Emerging Biomarkers for Asthma and Allergic Disease

D Vasileva, CMT Greenwood, D Daley - Genes, 2023 - mdpi.com
DNA methylation (DNAm) is a dynamic, age-dependent epigenetic modification that can be
used to study interactions between genetic and environmental factors. Environmental …