Interest in the role of the microbiome in human health has burgeoned over the past decade
with the advent of new technologies for interrogating complex microbial communities. The …

New tools for controlling tuberculosis are urgently needed. Despite our emerging
understanding of the biogeography of Mycobacterium tuberculosis, the implications for …

Accurate strain identification is essential for anyone working with bacteria. For many
species, multilocus sequence typing (MLST) is considered the “gold standard” of typing, but …

The stomach bacterium Helicobacter pylori is one of the most prevalent human pathogens. It
has dispersed globally with its human host, resulting in a distinct phylogeographic pattern …

Infection of the stomach by Helicobacter pylori is ubiquitous among humans. However,
although H. pylori strains from different geographic areas are associated with clear …

Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide.
Studies have reported human pathogens to have geographically structured population …

When modern humans left Africa ca. 60,000 years ago (60 kya), they were already infected
with Helicobacter pylori, and these bacteria have subsequently diversified in parallel with …

The human salivary microbiome may play a role in diseases of the oral cavity and interact
with microbiomes from other parts of the human body (in particular, the intestinal tract), but …

The evolutionary timing and spread of the Mycobacterium tuberculosis complex (MTBC),
one of the most successful groups of bacterial pathogens, remains largely unknown. Here …

Helicobacter pylori is the principal cause of gastric cancer, the second leading cause of
cancer mortality worldwide. However, H. pylori prevalence generally does not predict cancer …