The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
Boron cluster compounds as new chemical leads for antimicrobial therapy
Boron cluster compounds are inorganic compounds with chemical compositions and
structures vastly different from those of organic compounds, albeit with the ability to form a …
structures vastly different from those of organic compounds, albeit with the ability to form a …
Challenges and opportunities for the application of boron clusters in drug design
ZJ Lesnikowski - Journal of medicinal chemistry, 2016 - ACS Publications
There are two branches in boron medicinal chemistry: the first focuses on single boron atom
compounds, and the second utilizes boron clusters. Boron clusters and their heteroatom …
compounds, and the second utilizes boron clusters. Boron clusters and their heteroatom …
Boron science
NS Hosmane - New technologies and applications, 2011 - api.taylorfrancis.com
What is boron? The question itself may not seem very significant to many people. Their
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …
Boron in drug discovery: carboranes as unique pharmacophores in biologically active compounds
F Issa, M Kassiou, LM Rendina - Chemical reviews, 2011 - ACS Publications
Boron, in the form of boric acid, has played a role in medicine as a mild antiseptic and an
eye wash since its preparation from borax in the 18th century. However, the use of boron in …
eye wash since its preparation from borax in the 18th century. However, the use of boron in …
Boron containing compounds as protease inhibitors
R Smoum, A Rubinstein, VM Dembitsky… - Chemical …, 2012 - ACS Publications
Proteases form one of the largest and more important groups of enzymes. They selectively
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …
Facile Construction of New Hybrid Conjugation via Boron Cage Extension
F Sun, S Tan, HJ Cao, C Lu, D Tu… - Journal of the …, 2023 - ACS Publications
Aromatic polycyclic systems have been extensively utilized as structural subunits for the
preparation of various functional molecules. Currently, aromatics-based polycyclic systems …
preparation of various functional molecules. Currently, aromatics-based polycyclic systems …
Cobalt complexes as antiviral and antibacterial agents
EL Chang, C Simmers, DA Knight - Pharmaceuticals, 2010 - mdpi.com
Metal ion complexes are playing an increasing role in the development of antimicrobials. We
review here the antimicrobial properties of cobalt coordination complexes in oxidation state …
review here the antimicrobial properties of cobalt coordination complexes in oxidation state …
Supramolecular chemistry of anionic boron clusters and its applications in biology
J Cebula, K Fink, J Boratyński… - Coordination Chemistry …, 2023 - Elsevier
It has been almost 50 years since the term “supramolecular chemistry” was coined to
describe chemistry beyond the molecule. Since its beginning, supramolecular chemistry has …
describe chemistry beyond the molecule. Since its beginning, supramolecular chemistry has …
Polyhedral boranes for medical applications: Current status and perspectives
IB Sivaev, VV Bregadze - European Journal of Inorganic …, 2009 - Wiley Online Library
This review focuses on the current status and perspectives of the application of polyhedral
boron hydrides in medicine. The main topics discussed are boron neutron capture therapy …
boron hydrides in medicine. The main topics discussed are boron neutron capture therapy …