A transdiagnostic review of neuroimaging studies of apathy and disinhibition in dementia
LM Jenkins, L Wang, H Rosen, S Weintraub - Brain, 2022 - academic.oup.com
Apathy and disinhibition are common and highly distressing neuropsychiatric symptoms
associated with negative outcomes in persons with dementia. This paper is a critical review …
associated with negative outcomes in persons with dementia. This paper is a critical review …
Associations of AT (N) biomarkers with neuropsychiatric symptoms in preclinical Alzheimer's disease and cognitively unimpaired individuals
The development of in vivo biomarkers of Alzheimer's disease (AD) has advanced the
diagnosis of AD from a clinical syndrome to a biological construct. The preclinical stage of …
diagnosis of AD from a clinical syndrome to a biological construct. The preclinical stage of …
Plasma β-amyloid in mild behavioural impairment–neuropsychiatric symptoms on the Alzheimer's continuum
R Miao, HY Chen, S Gill, J Naude… - Journal of geriatric …, 2022 - journals.sagepub.com
Introduction: Simple markers are required to recognize older adults at higher risk for
neurodegenerative disease. Mild behavioural impairment (MBI) and plasma β-amyloid (Aβ) …
neurodegenerative disease. Mild behavioural impairment (MBI) and plasma β-amyloid (Aβ) …
Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation
KD Onos, A Uyar, KJ Keezer, HM Jackson… - PLoS …, 2019 - journals.plos.org
Classical laboratory strains show limited genetic diversity and do not harness natural
genetic variation. Mouse models relevant to Alzheimer's disease (AD) have largely been …
genetic variation. Mouse models relevant to Alzheimer's disease (AD) have largely been …
[HTML][HTML] The role of neuropsychiatric symptoms in research diagnostic criteria for neurodegenerative diseases
J Cummings - The American Journal of Geriatric Psychiatry, 2021 - Elsevier
ABSTRACTNeuropsychiatric syndromes and symptoms play increasingly important roles in
research diagnostic criteria for neurodegenerative disorders. Diagnostic criteria were …
research diagnostic criteria for neurodegenerative disorders. Diagnostic criteria were …
Agitation and impulsivity in mid and late life as possible risk markers for incident dementia
DR Bateman, S Gill, S Hu, ED Foster… - … Research & Clinical …, 2020 - Wiley Online Library
To identify knowledge gaps regarding new‐onset agitation and impulsivity prior to onset of
cognitive impairment or dementia the International Society to Advance Alzheimer's …
cognitive impairment or dementia the International Society to Advance Alzheimer's …
A narrative review on mild behavioural impairment: an exploration into its scientific perspectives
M Cozza, V Boccardi - Aging clinical and experimental research, 2023 - Springer
In clinical practice, the admission of patients with late-onset psychological and behavioural
symptoms is frequent, regardless of the presence or absence of cognitive decline. These …
symptoms is frequent, regardless of the presence or absence of cognitive decline. These …
Anesthetic‐loaded nanodroplets with focused ultrasound reduces agitation in Alzheimer's mice
Objective Alzheimer's disease (AD) is often associated with neuropsychiatric symptoms,
including agitation and aggressive behavior. These symptoms increase with disease …
including agitation and aggressive behavior. These symptoms increase with disease …
Agitation, oxidative stress, and cytokines in Alzheimer disease: biomarker analyses from a clinical trial with nabilone for agitation
M Ruthirakuhan, N Herrmann… - Journal of Geriatric …, 2020 - journals.sagepub.com
The endocannabinoid system has been a target of interest for agitation in Alzheimer disease
(AD) because of potential behavioral effects and its potential impact on mechanisms …
(AD) because of potential behavioral effects and its potential impact on mechanisms …
Analysis of whole-exome sequencing data for Alzheimer disease stratified by APOE genotype
Importance Previous genome-wide association studies of common variants identified
associations for Alzheimer disease (AD) loci evident only among individuals with …
associations for Alzheimer disease (AD) loci evident only among individuals with …