A review of automated microinjection systems for single cells in the embryogenesis stage

S Permana, E Grant, GM Walker… - … /ASME Transactions on …, 2016 - ieeexplore.ieee.org
Modern genetics research has resulted in significant advances in cell in vitro microinjection
systems. Such systems provide biological and medical practitioners with high volume cell …

A fully automated robotic system for microinjection of zebrafish embryos

W Wang, X Liu, D Gelinas, B Ciruna, Y Sun - PloS one, 2007 - journals.plos.org
As an important embodiment of biomanipulation, injection of foreign materials (eg, DNA,
RNAi, sperm, protein, and drug compounds) into individual cells has significant implications …

Robotic ICSI (intracytoplasmic sperm injection)

Z Lu, X Zhang, C Leung, N Esfandiari… - IEEE Transactions …, 2011 - ieeexplore.ieee.org
This paper is the first report of robotic intracytoplasmic sperm injection (ICSI). ICSI is a
clinical procedure performed worldwide in fertility clinics, requiring pick-up of a single sperm …

[HTML][HTML] Recent advances in critical nodes of embryo engineering technology

Y Ma, M Gu, L Chen, H Shen, Y Pan, Y Pang, S Miao… - Theranostics, 2021 - ncbi.nlm.nih.gov
The normal development and maturation of oocytes and sperm, the formation of fertilized
ova, the implantation of early embryos, and the growth and development of foetuses are the …

Vision-servo system for automated cell injection

Y Zhang, KK Tan, S Huang - IEEE Transactions on Industrial …, 2008 - ieeexplore.ieee.org
Recent developments in nuclear reprogramming and intracytoplasmic sperm injection reflect
an increasing need for more advanced and automatic micromanipulation technologies. In …

High-throughput automated injection of individual biological cells

WH Wang, XY Liu, Y Sun - IEEE Transactions on automation …, 2008 - ieeexplore.ieee.org
The ability of efficiently delivering soluable/insoluable drug compounds or biomolecules into
individual biological cells and quantifying their cellular responses is important for genetics …

Real-time deep learning-based image recognition for applications in automated positioning and injection of biological cells

F Sadak, M Saadat, AM Hajiyavand - Computers in Biology and Medicine, 2020 - Elsevier
Biological cell injection is an effective method in which a foreign material is directly
introduced into a biological cell. Since human involvement reduces the success rate of the …

Blastocyst microinjection automation

LS Mattos, E Grant, R Thresher… - IEEE Transactions on …, 2009 - ieeexplore.ieee.org
Blastocyst microinjections are routinely involved in the process of creating genetically
modified mice for biomedical research, but their efficiency is highly dependent on the skills …

Autonomous zebrafish embryo injection using a microrobotic system

WH Wang, XY Liu, Y Sun - 2007 IEEE International Conference …, 2007 - ieeexplore.ieee.org
As an important embodiment of biomanipulation, injection of foreign materials (eg, DNA,
RNAi, sperms, proteins, and drug compounds) into individual cells has significant …

A vision-based methodology to dynamically track and describe cell deformation during cell micromanipulation

F Karimirad, B Shirinzadeh, W Yan… - International Journal of …, 2013 - Taylor & Francis
The main objective of this article is to mechanize the procedure of tracking and describing
the various phases of deformation of a biological circular cell during micromanipulation. The …