[HTML][HTML] Cardiac toxicity of thoracic radiotherapy: existing evidence and future directions

K Banfill, M Giuliani, M Aznar, K Franks… - Journal of Thoracic …, 2021 - Elsevier
The impact of radiotherapy on the heart has become an area of interest in recent years.
Many different cardiac dose-volume constraints have been associated with cardiac toxicity …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T López-Fernández, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Association of left anterior descending coronary artery radiation dose with major adverse cardiac events and mortality in patients with non–small cell lung cancer

KM Atkins, TL Chaunzwa, N Lamba… - JAMA …, 2021 - jamanetwork.com
Importance Radiotherapy accelerates coronary heart disease (CHD), but the dose to critical
cardiac substructures has not been systematically studied in lung cancer. Objective To …

Is the importance of heart dose overstated in the treatment of non-small cell lung cancer? A systematic review of the literature

TW Zhang, J Snir, RG Boldt, GB Rodrigues… - International Journal of …, 2019 - Elsevier
Purpose Some recent studies have suggested a relationship between cardiac dose and
mortality in non-small cell lung cancer (NSCLC), but others have reported conflicting data …

Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Consensus Document of the Acute CardioVascular Care (ACVC) …

SA Gevaert, S Halvorsen, PR Sinnaeve… - … Heart Journal Acute …, 2021 - academic.oup.com
Advances in treatment, common cardiovascular (CV) risk factors and the ageing of the
population have led to an increasing number of cancer patients presenting with acute CV …

[HTML][HTML] Novel methodology to investigate the effect of radiation dose to heart substructures on overall survival

A McWilliam, J Khalifa, EV Osorio, K Banfill… - International Journal of …, 2020 - Elsevier
Purpose For patients with lung cancer treated with radiation therapy, a dose to the heart is
associated with excess mortality; however, it is often not feasible to spare the whole heart …

[HTML][HTML] Mean heart dose is an inadequate surrogate for left anterior descending coronary artery dose and the risk of major adverse cardiac events in lung cancer …

KM Atkins, DS Bitterman, TL Chaunzwa… - International Journal of …, 2021 - Elsevier
Purpose Mean heart dose (MHD) over 10 Gy and left anterior descending (LAD) coronary
artery volume (V) receiving 15 Gy (V15Gy) greater than 10% can significantly increase the …

[HTML][HTML] The impact of radiation dose to heart substructures on major coronary events and patient survival after chemoradiation therapy for esophageal cancer

X Wang, NL Palaskas, BP Hobbs, J Abe, KT Nead… - Cancers, 2022 - mdpi.com
Simple Summary Whether it is necessary to evaluate the radiation exposure of cardiac
substructures when making radiotherapy plans is one of the current research hotspots. In …

[HTML][HTML] Dosimetric predictors of symptomatic cardiac events after conventional-dose chemoradiation therapy for inoperable NSCLC

N Yegya-Raman, K Wang, S Kim, M Reyhan… - Journal of thoracic …, 2018 - Elsevier
Introduction We hypothesized that higher cardiac doses correlates with clinically significant
cardiotoxicity after standard-dose chemoradiation therapy (CRT)(∼ 60 Gy) for inoperable …

Radiation and the heart: systematic review of dosimetry and cardiac endpoints

JR Niska, CS Thorpe, SM Allen… - Expert review of …, 2018 - Taylor & Francis
Introduction: Recent trials in radiotherapy have associated heart dose and survival,
inadequately explained by the existing literature for radiation-related late cardiac effects …