The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - Elsevier
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Strategies to increase nitric oxide signalling in cardiovascular disease

JO Lundberg, MT Gladwin, E Weitzberg - Nature reviews Drug …, 2015 - nature.com
Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Ischemia and reperfusion—from mechanism to translation

HK Eltzschig, T Eckle - Nature medicine, 2011 - nature.com
Ischemia and reperfusion–elicited tissue injury contributes to morbidity and mortality in a
wide range of pathologies, including myocardial infarction, ischemic stroke, acute kidney …

Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by the …

JM Neuberger, WO Bechstein, DRJ Kuypers… - …, 2017 - journals.lww.com
Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

Y Zhai, H Petrowsky, JC Hong, RW Busuttil… - Nature reviews …, 2013 - nature.com
Ischaemia–reperfusion injury (IRI) in the liver, a major complication of haemorrhagic shock,
resection and transplantation, is a dynamic process that involves the two interrelated phases …

[HTML][HTML] Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment

M Salvadori, G Rosso, E Bertoni - World journal of transplantation, 2015 - ncbi.nlm.nih.gov
Ischemia/reperfusion injury is an unavoidable relevant consequence after kidney
transplantation and influences short term as well as long-term graft outcome. Clinically …

[HTML][HTML] Hepatic ischemia reperfusion injury: A systematic review of literature and the role of current drugs and biomarkers

M Cannistrà, M Ruggiero, A Zullo, G Gallelli… - International journal of …, 2016 - Elsevier
Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

JO Lundberg, E Weitzberg, MT Gladwin - Nature reviews Drug …, 2008 - nature.com
The inorganic anions nitrate (NO3−) and nitrite (NO2−) were previously thought to be inert
end products of endogenous nitric oxide (NO) metabolism. However, recent studies show …

Protective effect of platinum nano-antioxidant and nitric oxide against hepatic ischemia-reperfusion injury

J Mu, C Li, Y Shi, G Liu, J Zou, DY Zhang… - Nature …, 2022 - nature.com
Therapeutic interventions of hepatic ischemia-reperfusion injury to attenuate liver
dysfunction or multiple organ failure following liver surgery and transplantation remain …

Nitric oxide in liver diseases

Y Iwakiri, MY Kim - Trends in Pharmacological sciences, 2015 - cell.com
Nitric oxide (NO) and its derivatives play important roles in the physiology and
pathophysiology of the liver. Despite its diverse and complicated roles, certain patterns of …