Cognition in corticobasal syndrome and progressive supranuclear palsy: a review
Corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP) represent
challenging neurodegenerative disorders for clinicians and nonclinical scientists alike …
challenging neurodegenerative disorders for clinicians and nonclinical scientists alike …
Distribution patterns of tau pathology in progressive supranuclear palsy
GG Kovacs, MJ Lukic, DJ Irwin, T Arzberger… - Acta …, 2020 - Springer
Progressive supranuclear palsy (PSP) is a 4R-tauopathy predominated by subcortical
pathology in neurons, astrocytes, and oligodendroglia associated with various clinical …
pathology in neurons, astrocytes, and oligodendroglia associated with various clinical …
Language impairment in progressive supranuclear palsy and corticobasal syndrome
KA Peterson, K Patterson, JB Rowe - Journal of neurology, 2021 - Springer
Although commonly known as movement disorders, progressive supranuclear palsy (PSP)
and corticobasal syndrome (CBS) may present with changes in speech and language …
and corticobasal syndrome (CBS) may present with changes in speech and language …
Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy
Alzheimer's disease and progressive supranuclear palsy (PSP) represent
neurodegenerative tauopathies with predominantly cortical versus subcortical disease …
neurodegenerative tauopathies with predominantly cortical versus subcortical disease …
Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial
AL Boxer, I Qureshi, M Ahlijanian, M Grundman… - The Lancet …, 2019 - thelancet.com
Background Progressive supranuclear palsy is a rare neurodegenerative disease
associated with dysfunctional tau protein. BIIB092 is a humanised monoclonal antibody that …
associated with dysfunctional tau protein. BIIB092 is a humanised monoclonal antibody that …
Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy
D Wagshal, S Sankaranarayanan, V Guss… - Journal of Neurology …, 2015 - jnnp.bmj.com
Background Elevated CSF τ is considered a biomarker of neuronal injury in newly
developed Alzheimer's disease (AD) and mild cognitive impairment (MCI) criteria. However …
developed Alzheimer's disease (AD) and mild cognitive impairment (MCI) criteria. However …
[HTML][HTML] In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies
Understanding the cellular underpinnings of neurodegeneration remains a challenge; loss
of synapses and dendritic arborization are characteristic and can be quantified in vivo, with …
of synapses and dendritic arborization are characteristic and can be quantified in vivo, with …
Parkinsonism and dementia
C Koros, L Stefanis, N Scarmeas - Journal of the Neurological Sciences, 2022 - Elsevier
The aim of the present review is to summarize literature data on dementia in parkinsonian
disorders. Cognitive decline and the gradual development of dementia are considered to be …
disorders. Cognitive decline and the gradual development of dementia are considered to be …
Fifty years of progressive supranuclear palsy
Fifty years ago, in 1963, at the American Neurological Association annual meeting in Atlantic
City, John Clifford Richardson, John Steele and Jerzy Olszewski presented eight patients …
City, John Clifford Richardson, John Steele and Jerzy Olszewski presented eight patients …
Is the phenotype designation by PSP-MDS criteria stable throughout the disease course and consistent with tau distribution?
J Sánchez-Ruiz de Gordoa, V Zelaya… - Frontiers in …, 2022 - frontiersin.org
Introduction The MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do
not discriminate the phenotype diversity. Our purpose was to search for …
not discriminate the phenotype diversity. Our purpose was to search for …