In recent years there has been tremendous progress towards deep molecular
characterization of cell types using single-cell transcriptome sequencing, creating so-called …

In recent years, there has been a revived appreciation for the importance of spatial context
and morphological phenotypes for both understanding disease progression and guiding …

Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric
imaging of cleared tissues. However, there is a need for a flexible system that can address …

With rapid developments in microscopy methods, highly versatile, robust and affordable
implementations are needed to enable rapid and wide adoption by the biological sciences …

Three-dimensional fluorescence-based imaging of living cells and organisms requires the
sample to be exposed to substantial excitation illumination energy, typically causing …

Light-sheet microscopy has become indispensable for imaging developing organisms, and
imaging from multiple directions (views) is essential to improve its spatial resolution. We …

Optical imaging is a powerful tool to visualise and measure neuronal activity. However, due
to the size and opacity of vertebrate brains it has until now been impossible to …

Recently developed descanned versions of the oblique light-sheet microscope promise to
enable high-frame rate volumetric imaging in a variety of convenient preparations. The …

Optical microscopy has vastly expanded the frontiers of structural and functional biology,
due to the non-invasive probing of dynamic volumes in vivo. However, traditional widefield …

Volumetric microscopic imaging data acquired at high speeds is often needed in studies of
soft matter. Several microscopy techniques exist for this purpose, but a relative newcomer is …