Optogenetics for light control of biological systems
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
'Liking'and 'wanting'in eating and food reward: Brain mechanisms and clinical implications
I Morales, KC Berridge - Physiology & behavior, 2020 - Elsevier
It is becoming clearer how neurobiological mechanisms generate 'liking'and
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …
[HTML][HTML] Cardiogenic control of affective behavioural state
Emotional states influence bodily physiology, as exemplified in the top-down process by
which anxiety causes faster beating of the heart,–. However, whether an increased heart …
which anxiety causes faster beating of the heart,–. However, whether an increased heart …
Integration of optogenetics with complementary methodologies in systems neuroscience
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …
Temporal evolution of cortical ensembles promoting remote memory retrieval
Memories of fearful events can last a lifetime. The prelimbic (PL) cortex, a subregion of
prefrontal cortex, plays a critical role in fear memory retrieval over time. Most studies have …
prefrontal cortex, plays a critical role in fear memory retrieval over time. Most studies have …
Next-generation probes, particles, and proteins for neural interfacing
Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …
and therapy. This two-way communication allows us to monitor the state of the brain and its …
[HTML][HTML] BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons
Optogenetic manipulation of neuronal activity through excitatory and inhibitory opsins has
become an indispensable experimental strategy in neuroscience research. For many …
become an indispensable experimental strategy in neuroscience research. For many …
[HTML][HTML] Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …
[HTML][HTML] The persistence and transience of memory
BA Richards, PW Frankland - Neuron, 2017 - cell.com
The predominant focus in the neurobiological study of memory has been on remembering
(persistence). However, recent studies have considered the neurobiology of forgetting …
(persistence). However, recent studies have considered the neurobiology of forgetting …
[HTML][HTML] Optogenetic tools for subcellular applications in neuroscience
The ability to study cellular physiology using photosensitive, genetically encoded molecules
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …