Chemistry and multibeneficial bioactivities of carvacrol (4-isopropyl-2-methylphenol), a component of essential oils produced by aromatic plants and spices

M Friedman - Journal of agricultural and food chemistry, 2014 - ACS Publications
Aromatic plants produce organic compounds that may be involved in the defense of plants
against phytopathogenic insects, bacteria, fungi, and viruses. One of these compounds …

Role of TRP channels in the cardiovascular system

Z Yue, J Xie, AS Yu, J Stock, J Du… - American Journal of …, 2015 - journals.physiology.org
The transient receptor potential (TRP) superfamily consists of a large number of
nonselective cation channels with variable degree of Ca2+-permeability. The 28 mammalian …

Spices: the savory and beneficial science of pungency

B Nilius, G Appendino - Reviews of Physiology, Biochemistry and …, 2013 - Springer
Spicy food does not only provide an important hedonic input in daily life, but has also been
anedoctically associated to beneficial effects on our health. In this context, the discovery of …

Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-κB and caspase-3 regulation in the male rat …

E Abbasloo, S Amiresmaili, S Shirazpour… - Scientific Reports, 2023 - nature.com
Traumatic brain injury (TBI) causes progressive dysfunction that induces biochemical and
metabolic changes that lead to cell death. Nevertheless, there is no definitive FDA-approved …

The longitudinal biochemical profiling of TBI in a drop weight model of TBI

A Yilmaz, S Liraz-Zaltsman, E Shohami… - Scientific reports, 2023 - nature.com
Traumatic brain injury (TBI) is a major cause of mortality and disability worldwide,
particularly among individuals under the age of 45. It is a complex, and heterogeneous …

Traumatic brain injury using mouse models

YP Zhang, J Cai, LBE Shields, N Liu, XM Xu… - Translational stroke …, 2014 - Springer
The use of mouse models in traumatic brain injury (TBI) has several advantages compared
to other animal models including low cost of breeding, easy maintenance, and innovative …

Therapeutics to treat psychiatric and neurological disorders: A promising perspective from algerian traditional medicine

F Larit, F León - Plants, 2023 - mdpi.com
Ancient people sought out drugs in nature to prevent, cure, and treat their diseases,
including mental illnesses. Plants were their primary source for meeting their healthcare …

TRP modulation by natural compounds

FC Meotti, E Lemos de Andrade, JB Calixto - … Transient Receptor Potential …, 2014 - Springer
The use of medicinal plants or other naturally derived products to relieve illness can be
traced back over several millennia, and these natural products are still extensively used …

[HTML][HTML] Carvacrol prevents impairments in motor and neurochemical parameters in a model of progressive parkinsonism induced by reserpine

LCRF Lins, MF Souza, JMM Bispo, AM Gois… - Brain Research …, 2018 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease characterized by a progressive
degeneration of dopaminergic neurons in the substantia nigra pars compact (SNpc), with …

A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice

A Godinat, HM Park, SC Miller, K Cheng… - ACS chemical …, 2013 - ACS Publications
The discovery of biocompatible reactions had a tremendous impact on chemical biology,
allowing the study of numerous biological processes directly in complex systems. However …