What do DNA methylation studies tell us about depression? A systematic review

M Li, C D'Arcy, X Li, T Zhang, R Joober… - Translational psychiatry, 2019 - nature.com
There has been a limited number of systematic reviews conducted to summarize the
overview of the relationship between DNA methylation and depression, and to critically …

5-HT systems: emergent targets for memory formation and memory alterations

A Meneses - Reviews in the Neurosciences, 2013 - degruyter.com
Drugs acting through 5-hydroxytryptamine (serotonin or 5-HT) systems modulate memory
and its alterations, although the mechanisms involved are poorly understood. 5-HT drugs …

Genome-wide methylation study on depression: differential methylation and variable methylation in monozygotic twins

A Córdova-Palomera, M Fatjó-Vilas, C Gastó… - Translational …, 2015 - nature.com
Depressive disorders have been shown to be highly influenced by environmental
pathogenic factors, some of which are believed to exert stress on human brain functioning …

Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats

ME Glover, PC Pugh, NL Jackson, JL Cohen, AD Fant… - Neuroscience, 2015 - Elsevier
Selective serotonin reuptake inhibitor (SSRI) antidepressants are the mainstay treatment for
the 10–20% of pregnant and postpartum women who suffer major depression, but the effects …

Antidepressants and the adolescent brain

L Cousins, IM Goodyer - Journal of Psychopharmacology, 2015 - journals.sagepub.com
Major unipolar depression is a significant global health problem, with the highest incident
risk being during adolescence. A depressive illness during this period is associated with …

Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts

L Wang, P Yang, C Yang, D Yang, X Wu, T Cao… - European Archives of …, 2022 - Springer
Neurotransmitter metabolism plays a critical role in the pathophysiology of major depressive
disorder (MDD). However, whether the neurotransmitter metabolism in adolescent MDD is …

[HTML][HTML] Kefir peptides exhibit antidepressant-like activity in mice through the BDNF/TrkB pathway

HL Chen, YW Lan, MY Tu, YT Tung, MNY Chan… - Journal of Dairy …, 2021 - Elsevier
Depression is a prevalent, stress-related mental disorder that can lead to serious psychiatric
diseases with morbidity and high mortality. Although some functional fermented dairy drinks …

The role of cathepsins in memory functions and the pathophysiology of psychiatric disorders

C Niemeyer, N Matosin, D Kaul, A Philipsen… - Frontiers in …, 2020 - frontiersin.org
Cathepsins are proteases with functions in cellular homeostasis, lysosomal degradation and
autophagy. Their role in the development of neurodegenerative diseases has been …

Nicotine and fluoxetine alter adolescent dopamine-mediated behaviors via 5-HT1A receptor activation

M Yuan, FM Leslie - Frontiers in Psychiatry, 2024 - frontiersin.org
Introduction Abuse or misuse of tobacco, e-cigarettes, or antidepressants may have serious
clinical consequences during adolescence, a sensitive period during brain development …

Perinatal exposure to the SSRI paroxetine alters the methylome landscape of the developing dentate gyrus

ME Glover, CR McCoy, EA Shupe… - European Journal of …, 2019 - Wiley Online Library
Evidence in humans and rodents suggests that perinatal exposure to selective serotonin
reuptake inhibitor (SSRI) antidepressants can have serious long‐term consequences in …