D-amino acids may play key roles for specific physiological functions in different organs
including the brain. Importantly, D-amino acids have been detected in several neurological …

The absolute configuration dictates the biological role of chiral molecules in the living world.
This is best exemplified by all ribosomally synthesized polypeptides having chiral amino …

The bacterial strain is key to fermentation, and the intestinal tract in livestock and poultry is a
resource bank of good natural strains. The objective of this study was to evaluate the effect …

Colorectal cancer (CRC) is a common malignant tumor in the gastrointestinal tract. Changes
in amino acid metabolites have been implicated in tumorigenesis and disease progression …

Given the continuous increase in antibiotic resistance, research has been driven towards the
isolation of new antimicrobial molecules. Short, charged, and very hydrophobic antimicrobial …

Abstract Chinese Hamster Ovary cells (CHO) have become the most common workhorse for
the commercial production of therapeutic proteins, as well as for the production of …

α-amino acids exist in two configurations, named D-(dextro) and L-(levo) enantiomers. L-
amino acids are used in protein synthesis and play a central role in cell metabolism. The …

免疫检查点抑制剂(immune checkpoint inhibitors, ICIs) 疗法是目前最重要的抗肿瘤治疗方法,
但免疫治疗耐药现象严重影响着治疗效果. 本文拟对免疫检查点抑制剂耐药相关机制和肠道 …

Diosgenin (DIO) is an aglycone of steroid saponins acquired from plants, including
Dioscorea alata, Smilax China, and Trigonella foenum graecum, acting as an anti …