Self‐assembly of DNA nanostructures in different cations
The programmable nature of DNA allows the construction of custom‐designed static and
dynamic nanostructures, and assembly conditions typically require high concentrations of …
dynamic nanostructures, and assembly conditions typically require high concentrations of …
Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs
Literature conclusively shows that one of the quinolinequinone analogs (6-anilino-5, 8-
quinolinequinone), referred to as LY83583 hereafter, an inhibitor of guanylyl cyclase, was …
quinolinequinone), referred to as LY83583 hereafter, an inhibitor of guanylyl cyclase, was …
Structure based design, synthesis, and evaluation of anti-CML activity of the quinolinequinones as LY83583 analogs
Quinone-based small molecules are the promising structures for antiproliferative drug
design and can induce apoptosis in cancer cells. Among them, one of the …
design and can induce apoptosis in cancer cells. Among them, one of the …
New trinuclear nickel (II) complexes as potential topoisomerase I/IIα inhibitors: in vitro DNA binding, cleavage and cytotoxicity against human cancer cell lines
Nickel (II) complexes containing p-substitute (–H,–CI,–CH3,–OCH3)
isonitrosoacetophenone-based bis (oxime) ligands were synthesized by metal template …
isonitrosoacetophenone-based bis (oxime) ligands were synthesized by metal template …
Advancement in SARS-CoV-2 diagnosis: A new and stable electrochemical biosensor for genomic RNA detection
JAL Gomide, ACR Moço, LTR Tanaka… - …, 2025 - Elsevier
Abstract Coronavirus disease (COVID-19) is caused by infection with the SARS-CoV-2 virus,
having already caused more than seven million deaths worldwide. Conventional techniques …
having already caused more than seven million deaths worldwide. Conventional techniques …
Structural and biological characterization of anticancer nickel (II) bis (benzimidazole) complex
L Masaryk, B Tesarova, D Choquesillo-Lazarte… - Journal of Inorganic …, 2021 - Elsevier
In the present study, nickel (II) complex with 2-[2-[2-(1H-benzimidazol-2-yl) ethylsulfanyl]
ethyl]-1H-benzimidazole (tebb) of formula [Ni (tebb) 2](ClO 4) 2 has been prepared and its …
ethyl]-1H-benzimidazole (tebb) of formula [Ni (tebb) 2](ClO 4) 2 has been prepared and its …
In vitro and in silico assessment of antitumor properties and biomolecular binding studies for two new complexes based on NiII bearing k2N, S-donor ligands
RL Farias, AMR Polez, DES Silva, RD Zanetti… - Materials Science and …, 2021 - Elsevier
This work deals with two new molecule-based materials, namely Ni II-complexes of general
formulae [Ni (L1) 2](Ni1) and [Ni (L2) 2](Ni2), where L1= trans-cinnamaldehyde-N (4)-methyl …
formulae [Ni (L1) 2](Ni1) and [Ni (L2) 2](Ni2), where L1= trans-cinnamaldehyde-N (4)-methyl …
Preparation, cytotoxic activity and DNA interaction studies of new platinum (II) complexes with 1, 10-phenanthroline and 5-alkyl-1, 3, 4-oxadiazol-2 (3H)-thione …
WA Souza, LMS Ramos, AM de Almeida… - Journal of Inorganic …, 2022 - Elsevier
This work describes the synthesis, characterization and in vitro anticancer activity of two
platinum (II) complexes of the type [Pt (L1) 2 (1, 10-phen)] 1 and [Pt (L2) 2 (1, 10-phen)] 2 …
platinum (II) complexes of the type [Pt (L1) 2 (1, 10-phen)] 1 and [Pt (L2) 2 (1, 10-phen)] 2 …
Anticancer agents based on Plastoquinone analogs with N-phenylpiperazine: Structure-activity relationship and mechanism of action in breast cancer cells
Dimethyl-1, 4-benzoquinones named as Plastoquinone (PQ) analogs have antiproliferative
activity and are promising new members of molecules that can be used to cope with cancer …
activity and are promising new members of molecules that can be used to cope with cancer …
Ni (ii)-polypyridyl complexes as potential DNA binders
Novel examples of homoleptic Ni (II)-polypyridyl complexes, 1–3, bearing six-membered
chelate rings of aliphatic and aromatic backbones were synthesized. The presence of …
chelate rings of aliphatic and aromatic backbones were synthesized. The presence of …