TFOS DEWS II sex, gender, and hormones report

DA Sullivan, EM Rocha, P Aragona, JA Clayton, J Ding… - The ocular …, 2017 - Elsevier
One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

[HTML][HTML] Do sex steroids exert sex-specific and/or opposite effects on gene expression in lacrimal and meibomian glands?

DA Sullivan, RV Jensen, T Suzuki, SM Richards - Molecular vision, 2009 - ncbi.nlm.nih.gov
Purpose We hypothesize that sex steroids induce sex-specific and/or opposite effects in the
lacrimal and meibomian glands and that these actions may influence the prevalence of dry …

[HTML][HTML] Androgen regulation of gene expression in human meibomian gland and conjunctival epithelial cells

P Khandelwal, S Liu, DA Sullivan - Molecular vision, 2012 - ncbi.nlm.nih.gov
Purpose Androgens exert a significant influence on the structure, function and/or
pathophysiology of the meibomian gland and conjunctiva. We sought to determine whether …

Dihydrotestosterone suppression of proinflammatory gene expression in human meibomian gland epithelial cells

A Sahin, Y Liu, WR Kam, RR Darabad, DA Sullivan - The ocular surface, 2020 - Elsevier
Purpose We discovered that dihydrotestosterone (DHT) decreases the ability of
lipopolysaccharide, a bacterial toxin, to stimulate the secretion of leukotriene B4, a potent …

Top‐down HPLC–ESI‐MS characterization of rat gliadoralin A, a new member of the family of rat submandibular gland glutamine‐rich proteins and potential substrate …

T Cabras, F Iavarone, D Pirolli… - Journal of separation …, 2013 - Wiley Online Library
During HPLC–ESI‐MS/MS analysis of rat submandibular saliva secreted under isoprenaline
stimulation, a protein with an experimental [M+ H] 1+= 10 544.24 m/z was detected …

Pathophysiology of Dry Eye Disease Using Human Models

PA Asbell, ÖÖ Uçakhan - Dry Eye Disease, 2023 - Elsevier
Dry eye disease (DED) is an umbrella term that represents a wide spectrum of disorders with
different clinical presentations and variable risk factors. Despite significant work, the …

Expression and localization of phosphodiesterase 2A in the submandibular gland of mice

K Adthapanyawanich, H Nakata, S Iseki - Archives of Oral Biology, 2018 - Elsevier
Objectives Phosphodiesterases comprise a superfamily of enzymes that hydrolyze and
inactivate cyclic AMP (cAMP) and/or cyclic GMP (cGMP), thereby regulating cellular …

Different expression and subcellular localization of vesicular inhibitory amino acid transporter in ducts of major salivary glands: An in situ study in mice

A Pidsaya, A Kamnate, J Sirisin, M Watanabe… - Archives of Oral …, 2020 - Elsevier
Objective The aim of this study was to clarify the mechanism of GABA (□-amino butyric acid)-
signaling in the salivary glands by localization of vesicular inhibitory amino acid transporter …

[图书][B] The molecular logic of pheromone stimulus coding in the mouse vomeronasal system

L Pont-Lezica - 2008 - search.proquest.com
Pheromones provide information on the age, gender, and reproductive and social status of
conspecifics. In rodents, perception of these chemical cues by the main olfactory and …