An Intelligent Redox‐Responsive DNA Circuit for Robust On‐Site Profiling of Glutathione‐MicroRNA Signaling Pathway

Y Wang, J Shang, Y He, Q Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Synthetic biochemical circuits (eg, DNA circuits) remain at the forefront of intracellular
biosensing tasks yet are hindered by the undesired off‐site activation and the accompanying …

UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response …

AD Patterson, H Li, GS Eichler, KW Krausz… - Analytical …, 2008 - ACS Publications
Global transcriptomic and proteomic profiling platforms have yielded important insights into
the complex response to ionizing radiation (IR). Nonetheless, little is known about the ways …

Current and emerging magnetic resonance-based techniques for breast cancer

A Chhetri, X Li, JV Rispoli - Frontiers in Medicine, 2020 - frontiersin.org
Breast cancer is the most commonly diagnosed cancer among women worldwide, and early
detection remains a principal factor for improved patient outcomes and reduced mortality …

Moving from conventional to adaptive risk stratification for oropharyngeal cancer

VC Sandulache, RP Kirby, SY Lai - Frontiers in Oncology, 2024 - frontiersin.org
Oropharyngeal cancer (OPC) poses a complex therapeutic dilemma for patients and
oncologists alike, made worse by the epidemic increase in new cases associated with the …

Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy

W Shao, J Gu, C Huang, D Liu, H Huang, Z Huang… - Molecular cancer, 2014 - Springer
Background Ambiguity in malignant transformation of glioma has made prognostic diagnosis
very challenging. Tumor malignant transformation is closely correlated with specific …

Cisplatin-stitched polysaccharide vesicles for synergistic cancer therapy of triple antagonistic drugs

NU Deshpande, M Jayakannan - Biomacromolecules, 2017 - ACS Publications
New cisplatin-stitched polysaccharide vesicular nanocarrier is developed for combination
therapy of three clinical important antagonistic drugs together to accomplish synergistic …

Triple block nanocarrier platform for synergistic cancer therapy of antagonistic drugs

B Surnar, M Jayakannan - Biomacromolecules, 2016 - ACS Publications
A unique biodegradable triple block nanocarrier (TBN) is designed and developed for
synergistic combination therapy of antagonistic drugs for cancer treatment. The TBN was …

Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation

NS Giallourou, IR Rowland, SD Rothwell… - European Journal of …, 2019 - Springer
Purpose Watercress is a rich source of phytochemicals with anticancer potential, including
phenethyl isothiocyanate (PEITC). We examined the potential for watercress extracts and …

Cellular Lactate Spectroscopy Using 1.5 Tesla Clinical Apparatus

A Truszkiewicz, D Bartusik-Aebisher… - International Journal of …, 2022 - mdpi.com
Cellular lactate is a key cellular metabolite and marker of anaerobic glycolysis. Cellular
lactate uptake, release, production from glucose and glycogen, and interconversion with …

Metabolomic studies of radiation‐induced apoptosis of human leukocytes by capillary electrophoresis‐mass spectrometry and flow cytometry: Adaptive cellular …

R Lee, P Britz‐McKibbin - Electrophoresis, 2010 - Wiley Online Library
There is growing interest in the development of new methods for elucidating the biological
effects of low‐dose exposure to ionizing radiation (IR) on human health. Herein, we …