Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological
role in vivo has been proposed to be the elimination of pathogenic microorganisms …

We survive because we adapted to a world of microorganisms. All our epithelial surfaces
participate in keeping up an effective barrier against microbes while not initiating ongoing …

Intracellular lipopolysaccharide from Gram-negative bacteria including Escherichia coli,
Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activates mouse …

The last decade led to the discovery and characterization of several human β-defensins.
Analysis of genomic information indicates that the number of β-defensin-like molecules …

Defensins are small antimicrobial peptides that are produced by leukocytes and epithelial
cells, and that have an important role in innate immunity. Recent advances in understanding …

BACKGROUND At the interface of the external environment and the mucosal surface of the
female reproductive tract (FRT) lies a first-line defense against pathogen invasion that …

Antimicrobial peptides have emerged as promising agents against antibiotic-resistant
pathogens. They represent essential components of the innate immunity and permit humans …

Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …

Dental caries is a major worldwide oral disease problem in children. Although caries are
known to be influenced by dietary factors, the disease results from a bacterial infection; thus …

ABSTRACT β-Defensins are small (3 to 5 kDa in size) secreted antimicrobial and antiviral
proteins that are components of innate immunity. β-Defensins are secreted by epithelial …