An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities
Antibiotic-resistant infections are predicted to kill 10 million people per year by 2050, costing
the global economy $100 trillion. Therefore, there is an urgent need to develop alternative …
the global economy $100 trillion. Therefore, there is an urgent need to develop alternative …
Cn‐AMP1: A new promiscuous peptide with potential for microbial infections treatment
The antimicrobial peptides (AMPs) are evolutionarily ancient molecules that act as
components of the innate immune system. Recently, it was demonstrated that a single AMP …
components of the innate immune system. Recently, it was demonstrated that a single AMP …
Characterization and Pharmacological Properties of a Novel Multifunctional Kunitz Inhibitor from Erythrina velutina Seeds
Inhibitors of peptidases isolated from leguminous seeds have been studied for their
pharmacological properties. The present study focused on purification, biochemical …
pharmacological properties. The present study focused on purification, biochemical …
JcTI-I: a novel trypsin inhibitor from Jatropha curcas seed cake with potential for bacterial infection treatment
HPS Costa, JTA Oliveira, DOB Sousa… - Frontiers in …, 2014 - frontiersin.org
Jatropha curcas seed cake is a low-value by-product resulting from biodiesel production.
The seed cake is highly toxic, but it has great potential for biotechnology applications as it is …
The seed cake is highly toxic, but it has great potential for biotechnology applications as it is …
Antimicrobial Activity of ILTI, a Kunitz‐Type Trypsin Inhibitor from Inga laurina (SW.) Willd
Over the last few years, a growing number of proteinase inhibitors have been isolated from
plants and particularly from seeds and have shown antimicrobial activity. A 20,000 Da serine …
plants and particularly from seeds and have shown antimicrobial activity. A 20,000 Da serine …
Exploiting the biological roles of the trypsin inhibitor from Inga vera seeds: a multifunctional Kunitz inhibitor
C da Silva Bezerra, CFR de Oliveira, OLT Machado… - Process …, 2016 - Elsevier
Here, the purification, biochemical and biological properties of a trypsin inhibitor from Inga
vera seeds (IVTI) are described. Partial amino acid sequence of IVTI showed that it belongs …
vera seeds (IVTI) are described. Partial amino acid sequence of IVTI showed that it belongs …
[PDF][PDF] Plant serine protease inhibitor (SPI): A potent player with bactericidal, fungicidal, nematicidal and antiviral properties
UN Mishra, MV Reddy, DT Prasad - Int J Chem Stud, 2020 - researchgate.net
This review describes plant originated serine protease inhibitors (SPIs) that target or inhibit
different families of serine proteases (SPs), protein-digesting enzymes of various pathogens …
different families of serine proteases (SPs), protein-digesting enzymes of various pathogens …
Purification and characterization of a stable Kunitz trypsin inhibitor from Trigonella foenum-graecum (fenugreek) seeds
R Oddepally, G Sriram, L Guruprasad - Phytochemistry, 2013 - Elsevier
Kunitz trypsin inhibitor was purified from the seeds of Trigonella foenum-graecum (TfgKTI)
belonging to fabaceae family by ammonium sulphate precipitation, cation exchange, gel …
belonging to fabaceae family by ammonium sulphate precipitation, cation exchange, gel …
Inhibitory effects of a Kunitz-type inhibitor from Pithecellobium dumosum (Benth) seeds against insect-pests' digestive proteinases
FPS Rufino, VMA Pedroso, JN Araujo… - Plant Physiology and …, 2013 - Elsevier
Pithecellobium dumosum is a tree belonging to the Mimosoideae subfamily that presents
various previously characterized Kunitz-type inhibitors. The present study provides a novel …
various previously characterized Kunitz-type inhibitors. The present study provides a novel …
Purification and Biochemical Characterization of a New Protease Inhibitor from Conyza dioscoridis with Antimicrobial, Antifungal and Cytotoxic Effects
The main objective of the current study was the extraction, purification, and biochemical
characterization of a protein protease inhibitor from Conyza dioscoridis. Antimicrobial …
characterization of a protein protease inhibitor from Conyza dioscoridis. Antimicrobial …