Although the introduction of universal pertussis immunisation in infants has greatly reduced
the number of reported cases in infants and young children, disease incidence has been …

The introduction of vaccination in the 1950s significantly reduced the morbidity and mortality
of pertussis. However, since the 1990s, a resurgence of pertussis has been observed in …

In 2005, two tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap)
vaccines were licensed and recommended for use in adults and adolescents in the United …

Recent pertussis resurgence in numerous countries may be driven by asymptomatic
infections. Most pertussis surveillance studies are cross-sectional and cannot distinguish …

In many clinical microbiology laboratories, nucleic acid amplification tests such as PCR have
become the routine methods for the diagnosis of pertussis. While PCR has greatly increased …

Objectives Pertussis is a highly transmissible acute respiratory infection caused by the
bacterial pathogen Bordetella pertussis. The purpose of this study was to develop a rapid …

The incidence of whooping cough in the US has been rising slowly since the 1970s, but the
pace of this has accelerated sharply since acellular pertussis vaccines replaced the earlier …

Novel, highly specific, and sensitive real-time polymerase chain reaction (PCR) assays
using 2 targets, insertion sequence (IS481) and pertussis toxin subunit 1 (ptxS1), were …

Pertussis, an acute respiratory infection caused by Bordetella pertussis, classically manifests
as a protracted cough illness. The incidence of pertussis in the United States has been …

The prevalence of pertussis in Tunisia remains undetermined essentially because of the
unavailability of a basic laboratory diagnostic service. Specific diagnostic tools were applied …