Expanding antibiotic, vaccine, and diagnostics development and access to tackle antimicrobial resistance
The increasing number of bacterial infections globally that do not respond to any available
antibiotics indicates a need to invest in—and ensure access to—new antibiotics, vaccines …
antibiotics indicates a need to invest in—and ensure access to—new antibiotics, vaccines …
CRISPR Diagnostics for WHO High-Priority Sexually Transmitted Infections
Sexually transmitted infections (STIs) pose a global health threat. Most of these infections
are curable if detected in a timely and accurate manner. In 2022, the World Health …
are curable if detected in a timely and accurate manner. In 2022, the World Health …
Recent advances in centrifugal microfluidics for point-of-care testing
H Yuan, Z Miao, C Wan, J Wang, J Liu, Y Li, Y Xiao… - Lab on a Chip, 2025 - pubs.rsc.org
Point-of-care testing (POCT) holds significant importance in the field of infectious disease
prevention and control, as well as personalized precision medicine. The emerging …
prevention and control, as well as personalized precision medicine. The emerging …
Role of HIV self-testing in strengthening HIV prevention services
HIV self-testing, which has been increasingly available since 2016, can substantially
enhance the uptake of HIV testing, especially for key populations. Clinical trials have …
enhance the uptake of HIV testing, especially for key populations. Clinical trials have …
Development of a Novel Fluorescent-Based Lateral Flow Assay for the Detection of Neisseria gonorrhoeae at the Point of Care
B Gleeson, J Piton, L Mazzola, S McHugh… - Sexually Transmitted …, 2024 - journals.lww.com
Background Neisseria gonorrhoeae (NG) has acquired significant resistance, primarily due
to extensive and unwarranted antibiotic utilization over several decades. This resistance has …
to extensive and unwarranted antibiotic utilization over several decades. This resistance has …
Preliminary clinical performance of a Cas13a-based lateral flow assay for detecting Neisseria gonorrhoeae in urine specimens
LT Allan-Blitz, G Adams, G Sanders, P Shah… - mSphere, 2024 - journals.asm.org
Nucleic acid amplification testing (NAAT) for N. gonorrhoeae is unavailable in resource-
limited settings. We previously developed a CRISPR-based lateral flow assay for detecting …
limited settings. We previously developed a CRISPR-based lateral flow assay for detecting …
Tackling antimicrobial resistance: recognising the proposed five blind spots can accelerate progress
Antimicrobial resistance (AMR), a huge global health threat, will be back in the spotlight
when the UN will conduct a second high-level meeting on AMR in September, 2024. Ahead …
when the UN will conduct a second high-level meeting on AMR in September, 2024. Ahead …
A lateral flow assay for Neisseria gonorrhoeae: a step forward for an inexpensive biomarker-based diagnosis of N gonorrhoeae at the point of care?
NP Pai, JAR Dillon - The Lancet, 2024 - thelancet.com
At least one million curable sexually transmitted infections (STIs) are acquired daily, and
their long-term consequences affect reproductive health, psychological health, neonatal …
their long-term consequences affect reproductive health, psychological health, neonatal …
[HTML][HTML] Clinical Performance of Cas13a-based Point-of-Care Lateral Flow Assay for Detecting Neisseria gonorrhoeae
LT Allan-Blitz, G Sanders, P Shah, G Adams… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background Diagnosis of Neisseria (N.) gonorrhoeae is dependent on nucleic acid
amplification testing (NAAT), which is not available in resource-limited settings where the …
amplification testing (NAAT), which is not available in resource-limited settings where the …
[HTML][HTML] Multi-repeat sequences identification using genome mining techniques for developing highly sensitive molecular diagnostic assay for the detection of …
Chlamydia trachomatis (C. trachomatis) is a common sexually transmitted infection (STI). In
2019, the World Health Organization reported about 131 million infections. The majority of …
2019, the World Health Organization reported about 131 million infections. The majority of …