This systematic review aims to find effectful healthcare strategies, with special focus on drug-
free interventions and physical therapy, as part of the treatment for sleep in patients with …

Background Recent studies have confirmed an association between pain and dementia.
Whether musculoskeletal pain in the spine, upper limbs, and lower limbs is associated with …

Cognitive impairment is a common comorbidity of chronic pain, significantly disrupting
patients' quality of life. Despite this comorbidity being clinically recognized, the underlying …

Introduction: Previous research indicates ethnic/race group differences in pain and
neurodegenerative diseases. Accounting for socioenvironmental factors reduces ethnic/race …

Patients with chronic pain commonly report impaired memory. Increasing evidence has
demonstrated that inhibition of neurogenesis by neuroinflammation plays a crucial role in …

BACKGROUND Chronic pain leads to tau accumulation and hippocampal atrophy, which
may be moderated through inflammation. In older men, we examined associations of chronic …

Introduction Dementia is one of the major global health issues among the aging population,
characterized clinically by a progressive decline in higher cognitive functions. This paper …

Objectives Fibromyalgia (FM) has been associated with decreased hippocampal volume;
however, the atrophy patterns of hippocampal subregions have not yet been identified. We …

Introduction Previous studies have suggested a correlation between hearing loss (HL) and
cortical alterations, but the specific brain regions that may be affected are unknown. Methods …

Objective Cognitive dysfunction is a common comorbidity in patients with chronic pain.
Activation of Liver X receptors (LXRs) plays a potential role in improving cognitive disorders …