MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that can post-
transcriptionally regulate the expression of various oncogenes and tumor suppressor genes …

Cancer/testis (CT) antigens are protein antigens with normal expression restricted to adult
testicular germ cells, and yet are aberrantly activated and expressed in a proportion of …

The abscopal effect is a phenomenon in which local radiotherapy is associated with the
regression of metastatic cancer at a distance from the irradiated site. The abscopal effect …

Toll/IL-1 receptor family members are central components of host defense mechanisms in a
variety of species. One well conserved element in their signal transduction is Ser/Thr …

Identifying tumor-cell-specific markers and elucidating their epigenetic regulation and spatial
heterogeneity provides mechanistic insights into cancer etiology. Here, we perform snRNA …

Chronic lymphocytic leukemia (CLL) is associated with a variety of immunologic
disturbances. Hypogammaglobulinemia and autoimmune phenomena are both often …

The crafting of genetic and biochemical techniques to identify cancer antigens yielded the
unexpected discovery that immune recognition of tumors regularly accompanies cancer …

The release of proteins from tumors triggers an immune response in cancer patients. These
tumor antigens arise from several mechanisms including tumor-specific alterations in protein …

Antigen targeted immunotherapies might represent a novel treatment for B-cell chronic
lymphocytic leukemia (B-CLL). We screened the mRNA expression of tumor-associated …

Atopic dermatitis (AD) is a chronic itching (pruritic) skin disease. It results from a complex
interplay between strong genetic and environmental factors. Genome screens of families …