Countercurrent separation of natural products: an update

JB Friesen, JB McAlpine, SN Chen… - Journal of natural …, 2015 - ACS Publications
This work assesses the current instrumentation, method development, and applications in
countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC) …

The isolation of water-soluble natural products–challenges, strategies and perspectives

RGS Berlinck, CM Crnkovic, JR Gubiani… - Natural Product …, 2022 - pubs.rsc.org
Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …

Magnoflorine—Isolation and the Anticancer Potential against NCI-H1299 Lung, MDA-MB-468 Breast, T98G Glioma, and TE671 Rhabdomyosarcoma Cancer Cells

E Okon, W Kukula-Koch, M Halasa, A Jarzab, M Baran… - Biomolecules, 2020 - mdpi.com
Magnoflorine (MGN) is a quaternary aporphine alkaloid that exhibits numerous therapeutic
properties, including neuropsychopharmacological, anti-anxiety, immunomodulatory, anti …

Assessing solute partitioning in deep eutectic solvent-based biphasic systems using the predictive thermodynamic model COSMO-RS

F Bezold, ME Weinberger, M Minceva - Fluid Phase Equilibria, 2017 - Elsevier
The prediction quality of COSMO-RS for the thermodynamic properties needed for the
design of a liquid-liquid chromatographic process was evaluated for systems containing …

Steady state preparative multiple dual mode counter-current chromatography: Productivity and selectivity. Theory and experimental verification

AE Kostanyan, AA Erastov - Journal of Chromatography A, 2015 - Elsevier
In the steady state (SS) multiple dual mode (MDM) counter-current chromatography (CCC),
at the beginning of the first step of every cycle the sample dissolved in one of the phases is …

Validation of a liquid chromatography coupled with tandem mass spectrometry method for the determination of drugs in wastewater using a three‐phase solvent …

R Pascale, G Bianco, D Coviello… - Journal of separation …, 2020 - Wiley Online Library
Pharmaceuticals constitute one of the most important emerging classes of environmental
pollutants. A three‐phase solvent system of water, water containing 0.1% of formic acid and …

Analytical, preparative, and industrial-scale separation of substances by methods of countercurrent liquid-liquid chromatography

AA Kostanyan, AA Voshkin, VV Belova - Molecules, 2020 - mdpi.com
Countercurrent liquid-liquid chromatographic techniques (CCC), similar to solvent
extraction, are based on the different distribution of compounds between two immiscible …

Solvent system selection strategies in countercurrent separation

Y Liu, JB Friesen, JB McAlpine, GF Pauli - Planta medica, 2015 - thieme-connect.com
The majority of applications in countercurrent and centrifugal partition chromatography,
collectively known as countercurrent separation, are dedicated to medicinal plant and …

The 8th international conference on counter-current chromatography held at Brunel University, London, UK, July 23–25, 2014

S Ignatova, I Sutherland - Journal of Chromatography A, 2015 - Elsevier
Abstract The 8th International Conference on Counter-current Chromatography (CCC2014)
was held at Brunel University London from July 23rd to 25th, 2014. It has been 14 years …

Simple equations to simulate closed-loop recycling liquid–liquid chromatography: Ideal and non-ideal recycling models

AE Kostanyan - Journal of Chromatography A, 2015 - Elsevier
The ideal (the column outlet is directly connected to the column inlet) and non-ideal
(includes the effects of extra-column dispersion) recycling equilibrium-cell models are used …