Depression is frequent in older individuals and is often associated with cognitive impairment
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …

Background: Depressive symptoms are common in older adults and associated with
increased morbidity and cognitive decline. These symptoms occur during preclinical and …

Depressive symptoms are reported by 20% of the population and are related to altered
functional integrity of large-scale brain networks. The link between moment-to-moment brain …

Background Late-life depression (LLD) is a common and serious mental disorder, whose
neural mechanisms are not yet fully understood. In this study, we aimed to characterize LLD …

Alterations in functional brain lateralization, often indicated by an increased prevalence of
left-and/or mixed-handedness, have been demonstrated in several psychiatric and …

Background Late-life depression (LLD) has been associated with alterations in intrinsic
functional networks, best characterized in the default mode network (DMN), cognitive control …

Late-life depression (LLD) is a major depressive disorder that affects someone after the age
of 60 years. LLD is frequently associated with inadequate response and remission from …

Background Distinguishing between trait-and state-like neural alternations in major
depressive disorder (MDD) may advance our understanding of this recurring disorder. We …

Background Treatment resistant depression (TRD) remains a clinical challenge, and finding
biomarkers that predict treatment response are a long sought goal to precisely indicate …

BackgroundThe age-related heterogeneity in major depressive disorder (MDD) has
received significant attention. However, the neural mechanisms underlying such …