Potential role of cellular senescence in pulmonary arterial hypertension
L Liu, Y Wei, S Giunta, Q He… - Clinical and Experimental …, 2022 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a rare and chronic lung vasculature disease
characterised by pulmonary vasculature remodelling, including abnormal proliferation of …
characterised by pulmonary vasculature remodelling, including abnormal proliferation of …
A Preliminary Inquiry Into the Potential Mechanism of Huang-Lian-Jie-Du Decoction in Treating Rheumatoid Arthritis via Network Pharmacology and Molecular …
C Li, J Pan, C Xu, Z Jin, X Chen - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Huang-Lian-Jie-Du decoction (HLJDD) has been widely applied to treat inflammation-
associated diseases for thousands of years in China. However, the concrete molecular …
associated diseases for thousands of years in China. However, the concrete molecular …
Molecular characterization and elucidation of pathways to identify novel therapeutic targets in pulmonary arterial hypertension
X Yao, T Jing, T Wang, C Gu, X Chen, F Chen… - Frontiers in …, 2021 - frontiersin.org
Background: Pulmonary arterial hypertension (PAH) is a life-threatening chronic
cardiopulmonary disease. However, there are limited studies reflecting the available …
cardiopulmonary disease. However, there are limited studies reflecting the available …
Identification of signal pathways and hub genes of pulmonary arterial hypertension by bioinformatic analysis
RQ Wei, WM Zhang, Z Liang, C Piao… - Canadian Respiratory …, 2022 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a progressive and complex pulmonary vascular
disease with poor prognosis. The aim of this study was to provide a new understanding of …
disease with poor prognosis. The aim of this study was to provide a new understanding of …
Comprehensive analysis and validation of novel immune and vascular remodeling related genes signature associated with drug interactions in pulmonary arterial …
J Wang, MN Uddin, R Wang, Y Gong, Y Wu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Previous studies revealed that the gene signatures are associated with the
modulation and pathogenesis of pulmonary arterial hypertension (PAH). However …
modulation and pathogenesis of pulmonary arterial hypertension (PAH). However …
[HTML][HTML] ECM2 and GLT8D2 in human pulmonary artery hypertension: fruits from weighted gene co-expression network analysis
Z Bai, L Xu, Y Dai, Q Yuan, Z Zhou - Journal of Thoracic Disease, 2021 - ncbi.nlm.nih.gov
Background Pulmonary artery hypertension (PAH) is an incurable disease with a high
mortality rate. Current medications ameliorate symptoms but cannot target adverse vascular …
mortality rate. Current medications ameliorate symptoms but cannot target adverse vascular …
Inhibition of KIF23 alleviates IPAH by targeting pyroptosis and proliferation of PASMCs
Z Wu, G Zhou, H Wang, P Yao - International Journal of Molecular …, 2022 - mdpi.com
Idiopathic pulmonary arterial hypertension (IPAH) is a progressive vascular disease with
high mortality and heritability. Pyroptosis is a novel form of programmed cell death, and it is …
high mortality and heritability. Pyroptosis is a novel form of programmed cell death, and it is …
Comparative transcriptional analysis of pulmonary arterial hypertension associated with three different diseases
W Wang, Z Jiang, D Zhang, L Fu, R Wan… - Frontiers in Cell and …, 2021 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a severe cardiovascular disorder with high
mortality. Multiple clinical diseases can induce PAH, but the underlying molecular …
mortality. Multiple clinical diseases can induce PAH, but the underlying molecular …
Idiopathic Pulmonary Arterial Hypertension: Network-Based Integration of Multi-Omics Data Reveals New Molecular Signatures and Candidate Drugs
C Kasavi - OMICS: A Journal of Integrative Biology, 2023 - liebertpub.com
Idiopathic pulmonary arterial hypertension (IPAH) is a progressive disease that affects the
pulmonary arteries, resulting in increased pulmonary vascular resistance and right …
pulmonary arteries, resulting in increased pulmonary vascular resistance and right …
Upregulation of the key biomarker kinesin family member 20A (KIF20A) is associated with pulmonary artery hypertension
L Li, Q Xue, M Zhang, Z Yang, D Wang, G Yan, Y Qiao… - Genomics, 2023 - Elsevier
Abstracts Objective Pulmonary artery hypertension (PAH) is a complex, fatal disease with
limited treatments. This study aimed to investigate possible key targets in PAH through …
limited treatments. This study aimed to investigate possible key targets in PAH through …