[HTML][HTML] The role of CLEC-2 and its ligands in thromboinflammation
D Meng, M Luo, B Liu - Frontiers in immunology, 2021 - frontiersin.org
C-type lectin-like receptor 2 (CLEC-2, also known as CLEC-1b) is expressed on platelets,
Kupffer cells and other immune cells, and binds to various ligands including the mucin-like …
Kupffer cells and other immune cells, and binds to various ligands including the mucin-like …
Optimal duration of dual antiplatelet therapy after percutaneous coronary intervention with drug eluting stents: meta-analysis of randomised controlled trials
EP Navarese, F Andreotti, V Schulze, M Kołodziejczak… - bmj, 2015 - bmj.com
Objective To assess the benefits and risks of short term (< 12 months) or extended (> 12
months) dual antiplatelet therapy (DAPT) versus standard 12 month therapy, following …
months) dual antiplatelet therapy (DAPT) versus standard 12 month therapy, following …
microRNAs distinctively regulate vascular smooth muscle and endothelial cells: functional implications in angiogenesis, atherosclerosis, and in-stent restenosis
G Santulli - microRNA: Basic Science: From Molecular Biology to …, 2015 - Springer
Endothelial cells (EC) and vascular smooth muscle cells (VSMC) are the main cell types
within the vasculature. We describe here how microRNAs (miRs)—noncoding RNAs that …
within the vasculature. We describe here how microRNAs (miRs)—noncoding RNAs that …
[HTML][HTML] Vascular smooth muscle cells stimulate platelets and facilitate thrombus formation through platelet CLEC-2: implications in atherothrombosis
O Inoue, K Hokamura, T Shirai, M Osada, N Tsukiji… - PLoS …, 2015 - journals.plos.org
The platelet receptor CLEC-2 is involved in thrombosis/hemostasis, but its ligand,
podoplanin, is expressed only in advanced atherosclerotic lesions. We investigated CLEC-2 …
podoplanin, is expressed only in advanced atherosclerotic lesions. We investigated CLEC-2 …
Green formulation of curcumin loaded lipid-based nanoparticles as a novel carrier for inhibition of post-angioplasty restenosis
Restenosis is one of the major complications affecting outcomes of percutaneous coronary
interventions. The aims of this study were to formulate curcumin (CUR) nanoparticles by …
interventions. The aims of this study were to formulate curcumin (CUR) nanoparticles by …
Noninvasive molecular ultrasound monitoring of vessel healing after intravascular surgical procedures in a preclinical setup
Objective—Cardiovascular interventions induce damage to the vessel wall making
antithrombotic therapy inevitable until complete endothelial recovery. Without a method to …
antithrombotic therapy inevitable until complete endothelial recovery. Without a method to …
Molecular ultrasound imaging of αvβ3-integrin expression in carotid arteries of pigs after vessel injury
Objectives Interventions such as balloon angioplasty can cause vascular injury leading to
platelet activation, thrombus formation, and inflammatory response. This induces vascular …
platelet activation, thrombus formation, and inflammatory response. This induces vascular …
EGCG regulates cell apoptosis of human umbilical vein endothelial cells grown on 316L stainless steel for stent implantation
J Wang, Y Wang, Y Zhao, J Zhao… - Drug Design …, 2021 - Taylor & Francis
Background Nowadays, medical grade 316L stainless steel (316L SS) is being widely used
for intravascular stents, and the drug-eluting stent (DES) system is able to significantly …
for intravascular stents, and the drug-eluting stent (DES) system is able to significantly …
Amphiphilic Core Cross-Linked Star Polymers for the Delivery of Hydrophilic Drugs from Hydrophobic Matrices
K Somszor, S Allison-Logan, F Karimi… - …, 2021 - ACS Publications
The delivery of hydrophilic drugs from hydrophobic polymers is a long-standing challenge in
the biomaterials field due to the limited solubility of the therapeutic agent within the polymer …
the biomaterials field due to the limited solubility of the therapeutic agent within the polymer …
Physicochemical characteristics of liposomes are decisive for their antirestenosis efficacy following local delivery
Aim: To develop an ameliorated sirolimus (SIR) liposome for intramural delivery, the effects
of various carrier physicochemical parameters on the antirestenosis efficacy were evaluated …
of various carrier physicochemical parameters on the antirestenosis efficacy were evaluated …