Nerve growth factor (NGF) is the founding member of the neurotrophins family of proteins. It
was discovered more than half a century ago through its ability to promote sensory and …

Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor
(BDNF) play multiple roles in different settings including neuronal development, function and …

Hereditary sensory and autonomic neuropathies (HSANs) are a clinically and genetically
heterogeneous group of disorders of the PNS. Progressive degeneration, predominantly of …

Messenger RNA (mRNA) carries genetic instructions to the cell machinery for the transient
production of antigens or therapeutic proteins and shows enormous potential in vaccine …

Understanding sporadic Alzheimer's disease (AD) onset and progression requires an
explanation of what triggers the common core of abnormal processing of the amyloid …

During adulthood, the neurotrophin Nerve Growth Factor (NGF) sensitizes nociceptors,
thereby increasing the response to noxious stimuli. The relationship between NGF and pain …

Nerve Growth Factor (NGF) is being considered as a therapeutic candidate for Alzheimer's
disease (AD) treatment but the clinical application is hindered by its potent pro-nociceptive …

Abstract Nerve Growth Factor (NGF) is a therapeutic candidate for Alzheimer's disease,
based on its well known actions on basal forebrain cholinergic neurons. However, because …

Introduction: Among the range of therapeutic protein candidates for new generation
treatments of neurological diseases, neurotrophic factors and recombinant antibodies hold …

Nerve growth factor (NGF) signaling is important in the development and functional
maintenance of nociceptors, but it also plays a central role in initiating and sustaining heat …