[HTML][HTML] Cryo-electron tomography: the resolution revolution and a surge of in situ virological discoveries
Y Hong, Y Song, Z Zhang, S Li - Annual Review of Biophysics, 2023 - annualreviews.org
The recent proliferation of cryo-electron tomography (cryo-ET) techniques has led to the cryo-
ET resolution revolution. Meanwhile, significant efforts have been made to improve the …
ET resolution revolution. Meanwhile, significant efforts have been made to improve the …
A hitchhiker's guide through the cell: the world according to the capsids of alphaherpesviruses
K Döhner, MC Serrero, A Viejo-Borbolla… - Annual Review of …, 2024 - annualreviews.org
The nucleoplasm, the cytosol, the inside of virions, and again the cytosol comprise the world
in which the capsids of alphaherpesviruses encounter viral and host proteins that support or …
in which the capsids of alphaherpesviruses encounter viral and host proteins that support or …
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons
The neuronal axon is packed with cytoskeletal filaments, membranes, and organelles, many
of which move between the cell body and axon tip. Here, we used cryo-electron tomography …
of which move between the cell body and axon tip. Here, we used cryo-electron tomography …
The role of nuclear pores and importins for herpes simplex virus infection
K Döhner, MC Serrero, B Sodeik - Current opinion in virology, 2023 - Elsevier
Highlights•Dynein and kinesin-1.•Importin α, importin β, nuclear pores, and
nucleoporins.•BoHV-1, HSV-1, PrV, and VZV.Microtubule transport and nuclear import are …
nucleoporins.•BoHV-1, HSV-1, PrV, and VZV.Microtubule transport and nuclear import are …
[HTML][HTML] Cryo-electron tomography of intact cardiac muscle reveals myosin binding protein-C linking myosin and actin filaments
Myosin binding protein C (MyBP-C) is an accessory protein of the thick filament in vertebrate
cardiac muscle arranged over 9 stripes of intervals of 430 Å in each half of the A-band in the …
cardiac muscle arranged over 9 stripes of intervals of 430 Å in each half of the A-band in the …
[HTML][HTML] A frame-by-frame glance at membrane fusion mechanisms: From viral infections to fertilization
Viral entry and fertilization are distinct biological processes that share a common
mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell …
mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell …
[HTML][HTML] The journey of herpesvirus capsids and genomes to the host cell nucleus
K Döhner, A Cornelius, MC Serrero, B Sodeik - Current Opinion in Virology, 2021 - Elsevier
Highlights•Herpesvirus capsid stabilization, capsid portal vertices and portal caps.•Getting
dynein-mediated capsid transport on microtubule roads.•The enigma of translocating from …
dynein-mediated capsid transport on microtubule roads.•The enigma of translocating from …
[HTML][HTML] Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection
Herpes simplex virus-1 (HSV-1) is a large, enveloped DNA virus and its assembly in the cell
is a complex multi-step process during which viral particles interact with numerous cellular …
is a complex multi-step process during which viral particles interact with numerous cellular …
[HTML][HTML] Imaging techniques for detecting prokaryotic viruses in environmental samples
Viruses are the most abundant biological entities on Earth with an estimate of 1031 viral
particles across all ecosystems. Prokaryotic viruses—bacteriophages and archaeal viruses …
particles across all ecosystems. Prokaryotic viruses—bacteriophages and archaeal viruses …
Three-dimensional insights into human enveloped viruses in vitro and in situ
Viruses can be enveloped or non-enveloped, and require a host cell to replicate and
package their genomes into new virions to infect new cells. To accomplish this task, viruses …
package their genomes into new virions to infect new cells. To accomplish this task, viruses …