Platelets produce platelet growth factors such as PDGF, IGF-1, EGF-, HGF, TGFβ, bFGF, and
VEGF, which are crucial in regulating all stages of the wound healing process. The source of …

Background: Platelet-rich plasma (PRP) is a blood-derived preparation whose use has
grown exponentially in orthopaedic practice. However, there remains an unclear …

Abstract Purpose of Review This review evaluates current clinical literature on the use of
platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP …

The clinical application of platelet-rich plasma (PRP) and other regenerative therapies in
sports, spine, and musculoskeletal medicine has soared in the last decade. Over this period …

Background: There has been a surge in high-level studies investigating platelet-rich plasma
(PRP) for tendon and ligament injuries. A number of meta-analyses have been published …

The Orthopaedic Section of the American Physical Therapy Association (APTA) has an
ongoing effort to create evidence-based practice guidelines for orthopaedic physical therapy …

Platelet-rich plasma (PRP) has been the subject of hundreds of publications in recent years.
Reports of its effects in tissue, both positive and negative, have generated great interest in …

Background Platelet‐rich therapies are being used increasingly in the treatment of
musculoskeletal soft tissue injuries such as ligament, muscle and tendon tears and …

Background Achilles tendinopathy is a common disease among both athletes and in the
general population in which the use of platelet-rich plasma has recently been increasing …

Tendinopathy is frequently associated with structural disorganization within the tendon. As
such, the clinical use of ultrasound and magnetic resonance imaging for tendinopathy has …