As the process that silences gene expression ensues during development, the stage is set
for the activity of Polycomb-repressive complex 2 (PRC2) to maintain these repressed gene …

A switch from a petroleum-based to a biobased economy requires the capacity to produce
both high-value low-volume and low-value high-volume products. Recent evidence supports …

Marine organisms' persistence hinges on the capacity for acclimatization and adaptation to
the myriad of interacting environmental stressors associated with global climate change. In …

Genome packaging by nucleosomes is a hallmark of eukaryotes. Histones and the pathways
that deposit, remove, and read histone modifications are deeply conserved. Yet, we lack …

In contemporary oceans diatoms are an important group of eukaryotic phytoplankton that
typically dominate in upwelling regions and at high latitudes. They also make significant …

Histone posttranslational modifications are key regulators of chromatin-associated
processes including gene expression, DNA replication and DNA repair. Monoubiquitinated …

Histones and associated chromatin proteins have essential functions in eukaryotic genome
organization and regulation. Despite this fundamental role in eukaryotic cell biology, we lack …

Diatoms are the world's most diverse group of algae, comprising at least 100,000 species.
Contributing~ 20% of annual global carbon fixation, they underpin major aquatic food webs …

It is generally considered that Polycomb Repressive Complex (PRC) 2 deposits the histone
mark H3K27me3 on silent protein-coding genes, while transposable elements are …

Diatoms are one of the most successful and ecologically important groups of eukaryotic
phytoplankton in the modern ocean. Deciphering their genomes is a key step towards better …