The endoplasmic reticulum (ER) is a multifunctional organelle required for lipid biosynthesis,
calcium storage, and protein folding and processing. A number of physiological and …

In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

The endoplasmic reticulum (ER) stress response constitutes a cellular process that can be
triggered by a great variety of conditions that cause imbalances in intracellular homeostasis …

TWIST1 is a transcription factor critical for development that can promote prostate cancer
metastasis. During embryonic development, TWIST1 and HOXA9 are coexpressed in mouse …

Pituitary tumors (PT) are mostly benign, although occasionally they demonstrate aggressive
behavior, invasion of surrounding tissues, rapid growth, resistance to conventional …

Simple Summary To this day, cancer remains a medical challenge despite the development
of cutting-edge diagnostic methods and therapeutics. Thus, there is a continual demand for …

The possible use of HIV protease inhibitors (HIV‐PI) as new therapeutic option for the
treatment of cancer primarily originated from their success in treating HIV‐related Kaposi's …

Twist1, a basic helix-loop-helix transcription factor, plays a key role during development and
is a master regulator of the epithelial–mesenchymal transition (EMT) that promotes cancer …

Objective: To review the mechanisms of anti-cancer activity of nelfinavir and other protease
inhibitors (PIs) based on evidences reported in the published literature. Methods: We …

Pituitary adenomas are common intracranial neoplasms. Patients with these tumors exhibit a
wide range of clinically challenging problems, stemming either from results of sellar mass …