Immunosenescence is a series of age-related changes that affect the immune system and,
with time, lead to increased vulnerability to infectious diseases. This Review addresses …

Exposure to ambient air pollution is a well-established determinant of health and disease.
The Lancet Commission on pollution and health concludes that air pollution is the leading …

Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

PM2. 5 particles in air pollution have been widely considered associated with respiratory
and cardiovascular diseases. Recent studies have shown that PM2. 5 can also cause …

The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

Accumulating data suggest that air pollution increases the risk of internalizing
psychopathology, including anxiety and depressive disorders. Moreover, the link between …

Background The FDA-approved small-molecule drug ibrutinib is an effective targeted
therapy for patients with chronic lymphocytic leukemia (CLL). Ibrutinib inhibits Bruton's …

Environmental pollution is a major cause of global mortality and burden of disease. All
chemical pollution forms together may be responsible for up to 12 million annual excess …

Background Emerging findings have increased concern that exposure to fine particulate
matter air pollution (aerodynamic diameter≤ 2.5 μm; PM 2.5) may be neurotoxic, even at …

Air pollution is regarded as an important risk factor for many diseases that affect a large
proportion of the human population. To date, accumulating reports have noted that …