Advances and challenges in skeletal muscle angiogenesis
IM Olfert, O Baum, Y Hellsten… - American journal of …, 2016 - journals.physiology.org
The role of capillaries is to serve as the interface for delivery of oxygen and removal of
metabolites to/from tissues. During the past decade there has been a proliferation of studies …
metabolites to/from tissues. During the past decade there has been a proliferation of studies …
C‐type lectin domain group 14 proteins in vascular biology, cancer and inflammation
The C‐type lectin domain (CTLD) group 14 family of transmembrane glycoproteins consist of
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …
A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …
on the responses of the neurovascular unit. Here, we report the development and …
Vascular CXCR4 limits atherosclerosis by maintaining arterial integrity: evidence from mouse and human studies
Background: The CXCL12/CXCR4 chemokine ligand/receptor axis controls (progenitor) cell
homeostasis and trafficking. So far, an atheroprotective role of CXCL12/CXCR4 has only …
homeostasis and trafficking. So far, an atheroprotective role of CXCL12/CXCR4 has only …
[HTML][HTML] CD248: A therapeutic target in cancer and fibrotic diseases
BA Teicher - Oncotarget, 2019 - ncbi.nlm.nih.gov
Abstract CD248/endosialin/TEM1 is a type 1 transmembrane glycoprotein found on the
plasma membrane of activated mesenchymal cells. CD248 functions during embryo …
plasma membrane of activated mesenchymal cells. CD248 functions during embryo …
Endosialin-expressing pericytes promote metastatic dissemination
C Viski, C König, M Kijewska, C Mogler, CM Isacke… - Cancer research, 2016 - AACR
Metastasis is a multistep process that is critically dependent on the interaction of
metastasizing tumor cells with cells in the local microenvironment. Within this tumor stroma …
metastasizing tumor cells with cells in the local microenvironment. Within this tumor stroma …
Isolation of CD248‐expressing stromal vascular fraction for targeted improvement of wound healing
E Brett, ER Zielins, M Chin, M Januszyk… - Wound Repair and …, 2017 - Wiley Online Library
Wound healing remains a global issue of disability, cost, and health. Addition of cells from
the stromal vascular fraction (SVF) of adipose tissue has been shown to increase the rate of …
the stromal vascular fraction (SVF) of adipose tissue has been shown to increase the rate of …
Transcriptomic analysis of 3D vasculature-on-a-chip reveals paracrine factors affecting vasculature growth and maturation
SY Tan, Q Jing, Z Leung, Y Xu, LKW Cheng, SST Tam… - Lab on a Chip, 2022 - pubs.rsc.org
In vitro models of vasculature are of great importance for modelling vascular physiology and
pathology. However, there is usually a lack of proper spatial patterning of interacting …
pathology. However, there is usually a lack of proper spatial patterning of interacting …
TEM1 up-regulates MMP-2 and promotes ECM remodeling for facilitating invasion and migration of uterine sarcoma
C Wu, W Sun, D Shen, H Li, X Tong, Y Guo - Discover Oncology, 2023 - Springer
Objectives To explore the correlation between tumor endothelial marker 1 (TEM1) and
matrix metalloproteinase 2 (MMP-2) in uterine sarcoma and their roles in the progression of …
matrix metalloproteinase 2 (MMP-2) in uterine sarcoma and their roles in the progression of …
Inhibition of platelet‐derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy
KB Sugg, MA Korn, DC Sarver, JF Markworth… - FEBS …, 2017 - Wiley Online Library
The platelet‐derived growth factor receptors alpha and beta (PDGFR α and PDGFR β) mark
fibroadipogenic progenitor cells/fibroblasts and pericytes in skeletal muscle, respectively …
fibroadipogenic progenitor cells/fibroblasts and pericytes in skeletal muscle, respectively …