Advances and challenges in skeletal muscle angiogenesis

IM Olfert, O Baum, Y Hellsten… - American journal of …, 2016 - journals.physiology.org
The role of capillaries is to serve as the interface for delivery of oxygen and removal of
metabolites to/from tissues. During the past decade there has been a proliferation of studies …

C‐type lectin domain group 14 proteins in vascular biology, cancer and inflammation

KA Khan, JL McMurray, F Mohammed… - The FEBS …, 2019 - Wiley Online Library
The C‐type lectin domain (CTLD) group 14 family of transmembrane glycoproteins consist of
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …

A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke

Z Lyu, J Park, KM Kim, HJ Jin, H Wu… - Nature biomedical …, 2021 - nature.com
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …

Vascular CXCR4 limits atherosclerosis by maintaining arterial integrity: evidence from mouse and human studies

Y Döring, H Noels, EPC Van Der Vorst, C Neideck… - Circulation, 2017 - Am Heart Assoc
Background: The CXCL12/CXCR4 chemokine ligand/receptor axis controls (progenitor) cell
homeostasis and trafficking. So far, an atheroprotective role of CXCL12/CXCR4 has only …

[HTML][HTML] CD248: A therapeutic target in cancer and fibrotic diseases

BA Teicher - Oncotarget, 2019 - ncbi.nlm.nih.gov
Abstract CD248/endosialin/TEM1 is a type 1 transmembrane glycoprotein found on the
plasma membrane of activated mesenchymal cells. CD248 functions during embryo …

Endosialin-expressing pericytes promote metastatic dissemination

C Viski, C König, M Kijewska, C Mogler, CM Isacke… - Cancer research, 2016 - AACR
Metastasis is a multistep process that is critically dependent on the interaction of
metastasizing tumor cells with cells in the local microenvironment. Within this tumor stroma …

Isolation of CD248‐expressing stromal vascular fraction for targeted improvement of wound healing

E Brett, ER Zielins, M Chin, M Januszyk… - Wound Repair and …, 2017 - Wiley Online Library
Wound healing remains a global issue of disability, cost, and health. Addition of cells from
the stromal vascular fraction (SVF) of adipose tissue has been shown to increase the rate of …

Transcriptomic analysis of 3D vasculature-on-a-chip reveals paracrine factors affecting vasculature growth and maturation

SY Tan, Q Jing, Z Leung, Y Xu, LKW Cheng, SST Tam… - Lab on a Chip, 2022 - pubs.rsc.org
In vitro models of vasculature are of great importance for modelling vascular physiology and
pathology. However, there is usually a lack of proper spatial patterning of interacting …

TEM1 up-regulates MMP-2 and promotes ECM remodeling for facilitating invasion and migration of uterine sarcoma

C Wu, W Sun, D Shen, H Li, X Tong, Y Guo - Discover Oncology, 2023 - Springer
Objectives To explore the correlation between tumor endothelial marker 1 (TEM1) and
matrix metalloproteinase 2 (MMP-2) in uterine sarcoma and their roles in the progression of …

Inhibition of platelet‐derived growth factor signaling prevents muscle fiber growth during skeletal muscle hypertrophy

KB Sugg, MA Korn, DC Sarver, JF Markworth… - FEBS …, 2017 - Wiley Online Library
The platelet‐derived growth factor receptors alpha and beta (PDGFR α and PDGFR β) mark
fibroadipogenic progenitor cells/fibroblasts and pericytes in skeletal muscle, respectively …