Olfactory receptors (ORs) form the most important chemosensory receptor family responsible
for our sense of smell in the nasal olfactory epithelium. This receptor family belongs to the …

A large portion of the human GPCRome is still in the dark and understudied, consisting even
of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion …

Structural and mechanistic studies on human odorant receptors (ORs), key in olfactory
signaling, are challenging because of their low surface expression in heterologous cells …

With approximately 400 encoding genes in humans, odorant receptors (ORs) are the largest
subfamily of class AG protein-coupled receptors (GPCRs). Despite its high relevance and …

Conformational changes as well as molecular determinants related to the activation and
inactivation of olfactory receptors are still poorly understood due to the intrinsic difficulties in …

Detecting external chemosensory cues via Class-A G protein-coupled receptors (GPCRs) is
essential for behavioral and biological functions, influencing animal evolution and …

The review article analyzes the literature data on the role of molecular olfactory receptors
(ORs) and cAMP in the topographic organization of the olfactory system. Sensory …

The perpetual struggle of living organisms to maintain their homeostasis despite an ever-
changing environment has pushed evolution towards ever greater complexity. Even early in …

The article analyzes the literature data on the role of molecular olfactory receptors (OR) and
cAMP in the formation of the topographic organization of the olfactory sensory system …

Аннотация В статье анализируются данные литературы, посвященные роли
молекулярных обонятельных рецепторов и цАМФ в формировании топографической …