Nearly 30 years of animal models to study amyotrophic lateral sclerosis: a historical overview and future perspectives

T Bonifacino, RA Zerbo, M Balbi, C Torazza… - International journal of …, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal, multigenic, multifactorial, and non-cell
autonomous neurodegenerative disease characterized by upper and lower motor neuron …

Is exposure to BMAA a risk factor for neurodegenerative diseases? A response to a critical review of the BMAA hypothesis

D Ra, B Sa, B Sl, M Js, M Sj, D DA, S Ew, KO, B Eb… - Neurotoxicity …, 2021 - Springer
In a literature survey, Chernoff et al.(2017) dismissed the hypothesis that chronic exposure
to β-N-methylamino-L-alanine (BMAA) may be a risk factor for progressive …

Systematic and state-of the science review of the role of environmental factors in Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's Disease

ME Newell, S Adhikari, RU Halden - Science of The Total Environment, 2022 - Elsevier
The etiology of sporadic amyotrophic lateral sclerosis (ALS) is still unclear. We evaluate
environmental factors suspected to be associated with ALS for their potential linkage to …

Swimming against ALS: How to model disease in zebrafish for pathophysiological and behavioral studies

NAS Oliveira, BR Pinho, JMA Oliveira - Neuroscience & Biobehavioral …, 2023 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that leads to
progressive disability and motor impairment. Existing therapies provide modest …

[HTML][HTML] In vitro and in vivo models of amyotrophic lateral sclerosis: an updated overview

AM Gois, DMF Mendonça, MAM Freire… - Brain Research Bulletin, 2020 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is a progressive, neurodegenerative disease
characterized by loss of upper motor neurons (UMN) and lower motor neurons (LMN) …

Diseases and disorders in fish due to harmful algal blooms

RS Shahmohamadloo, T Frenken… - Climate Change on …, 2023 - cabidigitallibrary.org
Diseases and Disorders in Fish due to Harmful Algal Blooms | Climate Change on Diseases and
Disorders of Finfish in Cage Culture Skip the header click to show the menu Menu Cart Login …

[HTML][HTML] Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS

NAS Oliveira, BR Pinho, J Pinto, PG de Pinho… - Free Radical Biology …, 2024 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which the death of
motor neurons leads to loss of muscle function. Additionally, cognitive and circadian …

50 years of research on α-amino-β-methylaminopropionic acid (β-methylaminoalanine)

PB Nunn - Phytochemistry, 2017 - Elsevier
The isolation of α-amino-β-methylaminopropionic acid from seeds of Cycas circinalis (now
C. micronesica Hill) resulted from a purposeful attempt to establish the cause of the profound …

Temperature-and chemical-induced neurotoxicity in zebrafish

M Toni, C Arena, C Cioni, G Tedeschi - Frontiers in Physiology, 2023 - frontiersin.org
Throughout their lives, humans encounter a plethora of substances capable of inducing
neurotoxic effects, including drugs, heavy metals and pesticides. Neurotoxicity manifests …

Metabolic profiling of zebrafish (Danio rerio) embryos by NMR spectroscopy reveals multifaceted toxicity of β-methylamino-L-alanine (BMAA)

U Roy, L Conklin, J Schiller, J Matysik, JP Berry… - Scientific reports, 2017 - nature.com
Abstract β-methylamino-L-alanine (BMAA) has been linked to several interrelated
neurodegenerative diseases. Despite considerable research, specific contributions of BMAA …