(1) Background: Colorectal cancer (CRC) is the third most common cancer and the second
leading cause of cancer-related mortality worldwide. Up to 50% of patients with CRC …

Colorectal cancer liver metastasis (CRLM) is one of the leading causes of death among
patients with colorectal cancer (CRC). Although immunotherapy has demonstrated …

Background Contemporary management of patients with synchronous colorectal cancer and
liver metastases is complex. The aim of this project was to provide a practical framework for …

Objective The systemic spread of colorectal cancer (CRC) is dominated by the portal system
and exhibits diverse patterns of metastasis without systematical genomic investigation. Here …

Importance Currently, surgical resection of distant metastatic lesions has become the
preferred treatment for select colorectal cancer (CRC) patients with liver metastasis (LM) …

Colorectal cancer is a frequent neoplasm in western countries, mainly due to dietary and
behavioral factors. Its incidence is growing in developing countries for the westernization of …

Simple Summary Colorectal cancer is the third most common cancer worldwide, and
approximately half of all diagnosed patients will develop liver metastases. The only curative …

Background The objective of this study was to assess trends in the use as well as the
outcomes of patients undergoing simultaneous versus staged resection for synchronous …

Background Approximately one-fifth of patients with colorectal cancer present with hepatic
metastases. There are limited prospective data on the outcomes of synchronous combined …

Background We sought to characterize the risk of postoperative complications relative to the
surgical approach and overall synchronous colorectal liver metastases tumor burden score …