Role of circular RNAs in brain development and CNS diseases

SL Mehta, RJ Dempsey, R Vemuganti - Progress in neurobiology, 2020 - Elsevier
In mammals, many classes of noncoding RNAs (ncRNAs) are expressed at a much higher
level in the brain than in other organs. Recent studies have identified a new class of ncRNAs …

Ovarian cancers: genetic abnormalities, tumor heterogeneity and progression, clonal evolution and cancer stem cells

U Testa, E Petrucci, L Pasquini, G Castelli, E Pelosi - Medicines, 2018 - mdpi.com
Four main histological subtypes of ovarian cancer exist: serous (the most frequent),
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

E Battistello, KA Hixon, DE Comstock, CK Collings… - Molecular cell, 2023 - cell.com
Highly coordinated changes in gene expression underlie T cell activation and exhaustion.
However, the mechanisms by which such programs are regulated and how these may be …

TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway

J Zheng, X Liu, Y Xue, W Gong, J Ma, Z Xi… - Journal of hematology & …, 2017 - Springer
Abstract Background Circular RNAs are a subgroup of non-coding RNAs and generated by
a mammalian genome. Herein, the expression and function of circular RNA circ-TTBK2 were …

Recent concepts of ovarian carcinogenesis: type I and type II

M Koshiyama, N Matsumura… - BioMed research …, 2014 - Wiley Online Library
Type I ovarian tumors, where precursor lesions in the ovary have clearly been described,
include endometrioid, clear cell, mucinous, low grade serous, and transitional cell …

Genomics to immunotherapy of ovarian clear cell carcinoma: unique opportunities for management

K Oda, J Hamanishi, K Matsuo, K Hasegawa - Gynecologic oncology, 2018 - Elsevier
Ovarian clear cell carcinoma (OCCC) is distinctive from other histological types of epithelial
ovarian cancer, with genetic/epigenetic alterations, a specific immune-related molecular …

Recent advances in understanding the metabolic plasticity of ovarian cancer: A systematic review

H Kobayashi - Heliyon, 2022 - cell.com
Epithelial ovarian cancer (EOC) is a gynecologic malignancy with a poor prognosis due to
resistance to first-line chemotherapeutic agents. Some cancer cells are primarily dependent …

Targeting the tumour microenvironment in platinum-resistant ovarian cancer

M Cummings, C Freer, NM Orsi - Seminars in cancer biology, 2021 - Elsevier
Ovarian cancer typically presents at an advanced stage, and although the majority of cases
initially respond well to platinum-based therapies, chemoresistance almost always occurs …

Clear cell carcinoma of the ovary

K Fujiwara, K Oda, M Takano… - Textbook of Uncommon …, 2017 - Wiley Online Library
Clear cell carcinoma of the ovary is a distinct histological subtype of epithelial ovarian
cancer characterized by mutations in ARID1A and PIK3CA. These malignancies account for …

Pathology of endometrioid and clear cell carcinoma of the ovary

O Fadare, V Parkash - Surgical pathology clinics, 2019 - surgpath.theclinics.com
This review is an appraisal of the current state of knowledge of 2 enigmatic histotypes of
ovarian carcinoma: endometrioid and clear cell carcinoma. Both show an association …