Urolithin (Uro) B is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranates …

Cardiovascular complications are considered one of the leading causes of morbidity and
mortality among diabetic patients. Diabetic cardiomyopathy (DCM) is a type of …

Cardiovascular complications are the leading cause of morbidity in diabetes. Oxidative
stress and inflammation are implicated in the development and progression of diabetic …

The potential protective effect of epigallocatechin-3-gallate (EGCG) on type 2 diabetes-
induced heart injury was investigated. A rat model of diabetes was achieved by injection of …

Cardiomyopathy and pancreatic injury are health issues associated with type 2 diabetes
mellitus (T2DM) and are characterized by elevated oxidative stress, inflammation and …

Epigallocatechin-gallate (EGCG) is an emerging natural therapy. This study examined the
cardioprotective effect of EGCG on isoproterenol-induced myocardial damage and …

Background Different chemical toxicants or natural toxins can damage human health
through various routes such as air, water, fruits, foods, and vegetables. Purpose Herbal …

Background: Pyroptosis is an inflammatory programmed cell death accompanied by
activation of inflammasomes and maturation of pro-inflammatory cytokines interleukin-1β (IL …

Diabetes remains one of the leading causes of deaths and co-morbidities in the world, with
tremendous human, social and economic costs. Therefore, despite therapeutics and …

Despite its effectiveness in treating inflammatory diseases and various malignancies,
methotrexate (MTX) is well known to cause hepatotoxicity, which involves increased …