Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Increasing evidence supports the notion that neuroinflammation plays a critical role in the
etiology of major depressive disorder (MDD), at least in a subset of patients. By virtue of their …

Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

The glycosides of two flavonoids, naringin and naringenin, are found in various citrus fruits,
bergamots, tomatoes, and other fruits. These phytochemicals are associated with multiple …

Depression is a mental illness that affects the normal lives of over 300 million people.
Unfortunately, about 30% to 40% of patients do not adequately respond to pharmacotherapy …

Geraniol is an acyclic isoprenoid monoterpenoid analogue that has been shown to elicit
neuroprotective functions, primarily through its ability to stimulate antioxidant and anti …

According to epidemiological research, as the population ages, neurological illnesses are
becoming a bigger issue. Despite improvements in the treatment of these diseases, there …

Numerous animal and human studies have assessed the relationship between polyphenols
and outcomes related to depression. However, no comprehensive synthesis of the main …

In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured
lipid carrier (NLC) was developed and delivered via the nasal route for depression …

Social defeat stress (SDS) due to changes in biochemical functions has been implicated in
the pathogenesis of affective and cognitive disorders. Employing pharmacological approach …