[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
The link between Alzheimer disease and metabolic syndrome: a mutual relationship and long rigorous investigation
HM Al-Kuraishy, MS Jabir, AK Albuhadily… - Ageing Research …, 2023 - Elsevier
It has been illustrated that metabolic syndrome (MetS) is associated with Alzheimer disease
(AD) neuropathology. Components of MetS including central obesity, hypertension, insulin …
(AD) neuropathology. Components of MetS including central obesity, hypertension, insulin …
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway
Y Yang, L Wang, C Zhang, Y Guo, J Li… - Chemical Biology & …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive
impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with …
impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with …
Insulin resistance as the molecular link between diabetes and Alzheimer's disease
MMI Abdalla - World Journal of Diabetes, 2024 - pmc.ncbi.nlm.nih.gov
Diabetes mellitus (DM) and Alzheimer's disease (AD) are two major health concerns that
have seen a rising prevalence worldwide. Recent studies have indicated a possible link …
have seen a rising prevalence worldwide. Recent studies have indicated a possible link …
Relationship between metabolic syndrome and bone health–an evaluation of epidemiological studies and mechanisms involved
Metabolic syndrome (MetS) and osteoporosis are two medical problems plaguing the
ageing populations worldwide. Though seemingly distinctive to each other, metabolic …
ageing populations worldwide. Though seemingly distinctive to each other, metabolic …
Insulin resistance and bioenergetic manifestations: Targets and approaches in Alzheimer's disease
Aim Insulin has a well-established role in cognition, neuronal detoxification and synaptic
plasticity. Insulin transduction affect neurotransmitter functions, influence bioenergetics and …
plasticity. Insulin transduction affect neurotransmitter functions, influence bioenergetics and …
Metabolic diffusion in Neuropathologies: the relevance of Brain-Liver Axis
S Vegas-Suárez, J Simón, ML Martínez-Chantar… - Frontiers in …, 2022 - frontiersin.org
Chronic liver diseases include a broad group of hepatic disorders from different etiologies
and with varying degrees of progression and severity. Among them, non-alcoholic fatty …
and with varying degrees of progression and severity. Among them, non-alcoholic fatty …
Shared signaling pathways in Alzheimer's and metabolic disease may point to new treatment approaches
'A peculiar severe disease process of the cerebral cortex'are the exact words used by A.
Alzheimer in 1906 to describe a patient's increasingly severe condition of memory loss …
Alzheimer in 1906 to describe a patient's increasingly severe condition of memory loss …
Wnt signaling rescues amyloid beta-induced gut stem cell loss
Patients with Alzheimer's disease suffer from a decrease in brain mass and a prevalence of
amyloid-β plaques. These plaques are thought to play a role in disease progression, but …
amyloid-β plaques. These plaques are thought to play a role in disease progression, but …
Targeting hypercoagulation to alleviate Alzheimer's disease progression in metabolic syndrome
Abstract Introduction Metabolic Syndrome (MetS) constitutes an important risk factor for
Alzheimer's disease (AD); however, the mechanism linking these two disorders has not …
Alzheimer's disease (AD); however, the mechanism linking these two disorders has not …