Spät, András, and László Hunyady. Control of Aldosterone Secretion: A Model for
Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; …

Inappropriate aldosterone and parathyroid hormone (PTH) secretion is strongly linked with
development and progression of cardiovascular (CV) disease. Accumulating evidence …

Neurosteroids are potent and effective neuromodulators that are synthesized from
cholesterol in the brain. These agents and their synthetic derivatives influence the function of …

Dynamic interactions between components of the outer (OM) and inner (IM) membranes
control a number of critical mitochondrial functions such as channeling of metabolites and …

The pituitary adrenocorticotropic hormone (ACTH) plays a pivotal role in homeostasis and
stress response and is thus the major component of the hypothalamo–pituitary–adrenal axis …

Animal and human studies support a clinically relevant interaction between aldosterone and
parathyroid hormone (PTH) levels and suggest an impact of the interaction on …

Cholesterol serves as the initial substrate for all steroid hormones synthesized in the body
regardless of the steroidogenic tissue or final steroid produced. The first steroid formed in …

In adrenal glomerulosa cells, angiotensin II (Ang II) and potassium stimulate aldosterone
synthesis through activation of the calcium messenger system. The rate-limiting step in …

The past decade has seen dramatic progress in our understanding of membrane contact
sites (MCS). Important examples of these are endoplasmic reticulum (ER)-mitochondria …

The purpose of this article is to review fundamentals in adrenal gland histophysiology. Key
findings regarding the important signaling pathways involved in the regulation of …