Analyzing high-dimensional cytometry data using FlowSOM

K Quintelier, A Couckuyt, A Emmaneel, J Aerts… - Nature protocols, 2021 - nature.com
The dimensionality of cytometry data has strongly increased in the last decade, and in many
situations the traditional manual downstream analysis becomes insufficient. The field is …

[HTML][HTML] Adipose tissue: understanding the heterogeneity of stem cells for regenerative medicine

WK Ong, S Chakraborty, S Sugii - Biomolecules, 2021 - mdpi.com
Adipose-derived stem cells (ASCs) have been increasingly used as a versatile source of
mesenchymal stem cells (MSCs) for diverse clinical investigations. However, their …

An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia

H Xie, C Heier, X Meng, L Bakiri… - Proceedings of the …, 2022 - National Acad Sciences
Cancer-associated cachexia (CAC) is a hypermetabolic syndrome characterized by
unintended weight loss due to the atrophy of adipose tissue and skeletal muscle. A …

[HTML][HTML] Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications

S Sharma, S Muthu, M Jeyaraman… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
With developments in the field of tissue engineering and regenerative medicine, the use of
biological products for the treatment of various disorders has come into the limelight among …

[HTML][HTML] Gene therapy in orthopaedics: progress and challenges in pre-clinical development and translation

RS Watson-Levings, GD Palmer, PP Levings… - … in Bioengineering and …, 2022 - frontiersin.org
In orthopaedics, gene-based treatment approaches are being investigated for an array of
common-yet medically challenging-pathologic conditions of the skeletal connective tissues …

[HTML][HTML] The composition of adipose-derived regenerative cells isolated from lipoaspirate using a point of care system does not depend on the subject's individual age …

C Schmitz, C Alt, AR Azares, DA Pearce, TR Facile… - Cells, 2022 - mdpi.com
Uncultured, unmodified, autologous, adipose-derived regenerative cells (UA-ADRCs) are a
safe and effective treatment option for various musculoskeletal pathologies. However, it is …

From stem cells to spiral arteries: A journey through early placental development

JL James, AL Boss, C Sun, HH Allerkamp, AR Clark - Placenta, 2022 - Elsevier
Early placental development lays the foundation of a healthy pregnancy, and numerous
tightly regulated processes must occur for the placenta to meet the increasing nutrient and …

Stromal vascular fraction with platelet‐rich plasma injection during surgery is feasible and safe in treatment‐refractory perianal fistulising Crohn's disease: A pilot study

JHC Arkenbosch, O van Ruler… - Alimentary …, 2023 - Wiley Online Library
Background An unmet need remains for improved management in perianal fistulising
Crohn's disease (pCD). Recently, local administration of adipose‐derived cells has shown …

[HTML][HTML] Characterization of adult human skeletal cells in different tissues reveals a CD90+ CD34+ periosteal stem/progenitor population

Y Cao, SM Bolam, AL Boss, HC Murray, JT Munro… - Bone, 2024 - Elsevier
The periosteum plays a crucial role in bone healing and is an important source of skeletal
stem and progenitor cells. Recent studies in mice indicate that diverse populations of …

Lipedema: The use of cultured adipocytes for identification of diagnostic markers

AM Ernst, M Steiner, V Kainz, H Tempfer… - Plastic and …, 2023 - journals.lww.com
Background: Lipedema, diagnosed most often in women, is a progressive disease
characterized by the disproportionate and symmetrical distribution of adipose tissue …