Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: A comprehensive review

B Lomonte - Toxicon, 2023 - Elsevier
Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …

Essential Oil of Cymbopogon nardus (L.) Rendle: A Strategy to Combat Fungal Infections Caused by Candida Species

LG De Toledo, MADS Ramos, L Spósito… - International Journal of …, 2016 - mdpi.com
Background: The incidence of fungal infections, especially those caused by Candida yeasts,
has increased over the last two decades. However, the indicated therapy for fungal control …

Natural products acting against S. aureus through membrane and cell wall disruption

G Kumar, K Engle - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2015 to 2022 Staphylococcus aureus (S. aureus) is responsible for several
community and hospital-acquired infections with life-threatening complications such as …

Adding functions to biomaterial surfaces through protein incorporation

MA Wronska, IB O'Connor, MA Tilbury… - Advanced …, 2016 - Wiley Online Library
The concept of biomaterials has evolved from one of inert mechanical supports with a long‐
term, biologically inactive role in the body into complex matrices that exhibit selective cell …

[HTML][HTML] In vitro and in vivo anti-Helicobacter pylori activity of Casearia sylvestris leaf derivatives

L Spósito, FB Oda, JH Vieira, FA Carvalho… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance The number of bacterial strains that are resistant to
multiple conventional antimicrobial agents is increasing. In this context, natural products …

Stability of the potent antioxidant peptide SNAAC identified from Spanish dry-cured ham

M Gallego, L Mora, M Reig, F Toldrá - Food Research International, 2018 - Elsevier
Antioxidant peptides positively regulate oxidative stress in the human body as well as delay,
retard or prevent protein and lipid oxidation in food products. Spanish dry-cured ham has …

[HTML][HTML] Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV-2 and papain-like protease inhibitors

MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches… - Molecules, 2021 - mdpi.com
The COVID-19 outbreak has rapidly spread on a global scale, affecting the economy and
public health systems throughout the world. In recent years, peptide-based therapeutics …

Past, present, and future of naturally occurring antimicrobials related to snake venoms

N Oguiura, L Sanches, PV Duarte, MA Sulca-López… - Animals, 2023 - mdpi.com
Simple Summary A critical global health problem is microbial resistance to antibiotics. In
order to further discuss this issue and search for practical means to overcome such …

Dimerization of antimicrobial peptides: a promising strategy to enhance antimicrobial peptide activity

EN Lorenzon, JP Piccoli… - Protein and peptide …, 2019 - ingentaconnect.com
Antimicrobial resistance is a global health problem with strong social and economic impacts.
The development of new antimicrobial agents is considered an urgent challenge. In this …