[HTML][HTML] Prevalence and risk factors of colorectal cancer in Asia
Globally, colorectal cancer (CRC) is a substantial public health burden, and it is increasingly
affecting populations in Asian countries. The overall prevalence of CRC is reported to be low …
affecting populations in Asian countries. The overall prevalence of CRC is reported to be low …
SNP-target genes interaction perturbing the cancer risk in the post-GWAS
W Yang, T Zhang, X Song, G Dong, L Xu, F Jiang - Cancers, 2022 - mdpi.com
Simple Summary Genome-wide association studies have identified a vast number of cancer
risk-associated loci harboring numerous single nucleotide polymorphisms that regulate …
risk-associated loci harboring numerous single nucleotide polymorphisms that regulate …
[HTML][HTML] Genome-wide modeling of polygenic risk score in colorectal cancer risk
M Thomas, LC Sakoda, M Hoffmeister… - The American journal of …, 2020 - cell.com
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying
individuals at low and high risk of developing CRC, as they can then be offered targeted …
individuals at low and high risk of developing CRC, as they can then be offered targeted …
Risk stratification for early-onset colorectal cancer using a combination of genetic and environmental risk scores: an international multi-center study
Background The incidence of colorectal cancer (CRC) among individuals aged younger
than 50 years has been increasing. As screening guidelines lower the recommended age of …
than 50 years has been increasing. As screening guidelines lower the recommended age of …
Interactions among lncRNAs, miRNAs and mRNA in colorectal cancer
XJ Tang, W Wang, SS Hann - Biochimie, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …
recently emerged as one of the largest and significantly diverse RNA families whereas …
The human immunopeptidome project: a roadmap to predict and treat immune diseases
JA Vizcaíno, P Kubiniok, KA Kovalchik, Q Ma… - Molecular & Cellular …, 2020 - ASBMB
The science that investigates the ensembles of all peptides associated to human leukocyte
antigen (HLA) molecules is termed" immunopeptidomics" and is typically driven by mass …
antigen (HLA) molecules is termed" immunopeptidomics" and is typically driven by mass …
Coding and regulatory variants are associated with serum protein levels and disease
V Emilsson, V Gudmundsdottir, A Gudjonsson… - Nature …, 2022 - nature.com
Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep
serum proteome survey recently revealed close associations between serum protein …
serum proteome survey recently revealed close associations between serum protein …
[HTML][HTML] Healthy lifestyles, genetic modifiers, and colorectal cancer risk: a prospective cohort study in the UK Biobank
Background Both genetic and lifestyle factors play an etiologic role in colorectal cancer
(CRC). Objectives We evaluated potential gene–environment interactions in CRC risk …
(CRC). Objectives We evaluated potential gene–environment interactions in CRC risk …
Prognostic model development for classification of colorectal adenocarcinoma by using machine learning model based on feature selection technique boruta
Colorectal cancer (CRC) is the third most prevalent cancer type and accounts for nearly one
million deaths worldwide. The CRC mRNA gene expression datasets from TCGA and GEO …
million deaths worldwide. The CRC mRNA gene expression datasets from TCGA and GEO …
Risk SNP-induced lncRNA-SLCC1 drives colorectal cancer through activating glycolysis signaling
Long non-coding RNAs (lncRNAs) play key roles in colorectal carcinogenesis. Here, we
aimed to identify the risk SNP-induced lncRNAs and to investigate their roles in colorectal …
aimed to identify the risk SNP-induced lncRNAs and to investigate their roles in colorectal …