Aquaculture is the fastest-growing food production area in the world and this productive
activity requires nutrients that fit the needs of cultured species, as well as additives or …

Conceptually and mechanistically, the evolution of multicellularity required the integration of
single cells into new functionally, reproductively and evolutionary stable multicellular …

How phenotypically distinct states in isogenic cell populations appear and stably co-exist
remains unresolved. We find that within a mature, clonal yeast colony developing in low …

The evolutionary transition from single-celled to multicellular growth is a classic and
intriguing problem in biology. Saccharomyces cerevisiae is a useful model to study …

Fungal pathogens pose an increasing threat to public health. Limited clinical drug regimens
and emerging drug-resistant isolates challenge infection control. The global burden of …

A cell population characterized by the release of glucose repression and known as [GAR+]
emerges spontaneously in the yeast Saccharomyces cerevisiae. This study revealed that the …

Understanding how and why cells cooperate to form multicellular organisms is a central aim
of evolutionary biology. Multicellular groups can form through clonal development (where …

To persist in variable environments, populations of microorganisms have to survive periods
of starvation and be able to restart cell division in nutrient-rich conditions. Typically …

Dormancy is a key survival strategy in many organisms across the tree of life. Organisms that
utilize some type of dormancy (hibernation, aestivation, brumation, diapause, and …

Background Compared to the oleaginous yeast Yarrowia lipolytica, Trichosporon cutaneum
can metabolize pentose sugars more efficiently, and in the meantime is more tolerant to …