Critical re‐evaluation of the identification of iron deficiency states and effective iron repletion strategies in patients with chronic heart failure
According to current guidelines, iron deficiency is defined by a serum ferritin level< 100
ng/ml or a transferrin saturation (TSAT)< 20% if the serum ferritin level is 100–299 μg/L …
ng/ml or a transferrin saturation (TSAT)< 20% if the serum ferritin level is 100–299 μg/L …
Identification of three mechanistic pathways for iron-deficient heart failure
Current understanding of iron-deficient heart failure is based on blood tests that are thought
to reflect systemic iron stores, but the available evidence suggests greater complexity. The …
to reflect systemic iron stores, but the available evidence suggests greater complexity. The …
3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models
Intracellular cargo delivery via distinct transport routes relies on vesicle carriers. A key
trafficking route distributes cargo taken up by clathrin-mediated endocytosis (CME) via early …
trafficking route distributes cargo taken up by clathrin-mediated endocytosis (CME) via early …
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy
R Wali, H Xu, C Cheruiyot, HN Saleem… - Biological …, 2024 - degruyter.com
Integration of multiple data sources presents a challenge for accurate prediction of
molecular patho-phenotypic features in automated analysis of data from human model …
molecular patho-phenotypic features in automated analysis of data from human model …