[HTML][HTML] Epilepsy-associated genes

J Wang, ZJ Lin, L Liu, HQ Xu, YW Shi, YH Yi, N He… - Seizure, 2017 - Elsevier
Abstract Development in genetic technology has led to the identification of an increasing
number of genes associated with epilepsy. These discoveries will both provide the basis for …

Deconstructing cortical folding: genetic, cellular and mechanical determinants

C Llinares-Benadero, V Borrell - Nature Reviews Neuroscience, 2019 - nature.com
Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …

[图书][B] Volpe's Neurology of the Newborn

JJ Volpe, TE Inder, BT Darras, LS de Vries… - 2017 - books.google.com
A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …

Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

Growth and folding of the mammalian cerebral cortex: from molecules to malformations

T Sun, RF Hevner - Nature Reviews Neuroscience, 2014 - nature.com
The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …

Proliferation control in neural stem and progenitor cells

CCF Homem, M Repic, JA Knoblich - Nature Reviews Neuroscience, 2015 - nature.com
Neural circuit function can be drastically affected by variations in the number of cells that are
produced during development or by a reduction in adult cell number owing to disease. For …

A developmental and genetic classification for malformations of cortical development: update 2012

AJ Barkovich, R Guerrini, RI Kuzniecky, GD Jackson… - Brain, 2012 - academic.oup.com
Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …

The genetics of primary microcephaly

D Jayaraman, BI Bae, CA Walsh - Annual review of genomics …, 2018 - annualreviews.org
Primary microcephaly (MCPH, for “microcephaly primary hereditary”) is a disorder of brain
development that results in a head circumference more than 3 standard deviations below …

Cerebral cortex expansion and folding: what have we learned?

V Fernández, C Llinares‐Benadero, V Borrell - The EMBO journal, 2016 - embopress.org
One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

W Zhang, SL Yang, M Yang, S Herrlinger… - Nature …, 2019 - nature.com
Primary microcephaly is caused by mutations in genes encoding centrosomal proteins
including WDR62 and KIF2A. However, mechanisms underlying human microcephaly …