Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer

F Bishehsari, RM Voigt, A Keshavarzian - Nature Reviews …, 2020 - nature.com
The metabolic syndrome is prevalent in developed nations and accounts for the largest
burden of non-communicable diseases worldwide. The metabolic syndrome has direct …

Emerging roles for branched-chain amino acid metabolism in cancer

S Sivanand, MG Vander Heiden - Cancer cell, 2020 - cell.com
Metabolic pathways must be adapted to support cell processes required for transformation
and cancer progression. Amino acid metabolism is deregulated in many cancers, with …

[HTML][HTML] Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care

M De Hert, CU Correll, J Bobes… - World …, 2011 - ncbi.nlm.nih.gov
The lifespan of people with severe mental illness (SMI) is shorter compared to the general
population. This excess mortality is mainly due to physical illness. We report prevalence …

Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies

S O'Neill, L O'Driscoll - Obesity reviews, 2015 - Wiley Online Library
Obesity is reaching epidemic proportions with recent worldwide figures estimated at 1.4
billion and rising year‐on‐year. Obesity affects all socioeconomic backgrounds and …

The role of obesity, type 2 diabetes, and metabolic factors in pancreatic cancer: a Mendelian randomization study

R Carreras-Torres, M Johansson… - JNCI: Journal of the …, 2017 - academic.oup.com
Background Risk factors for pancreatic cancer include a cluster of metabolic conditions such
as obesity, hypertension, dyslipidemia, insulin resistance, and type 2 diabetes. Given that …

Effects of hyperglycemia on the progression of tumor diseases

W Li, X Zhang, H Sang, Y Zhou, C Shang… - Journal of Experimental …, 2019 - Springer
Malignant tumors are often multifactorial. Epidemiological studies have shown that
hyperglycemia raises the prevalence and mortality of certain malignancies, like breast, liver …

Association between metabolic syndrome and cancer

M Uzunlulu, O Telci Caklili, A Oguz - Annals of Nutrition and Metabolism, 2016 - karger.com
Growing data show the association of metabolic syndrome (MetS) or its components with
cancer development and cancer-related mortality. It is suggested that in MetS and cancer …

[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …

SMH Chan, S Selemidis, S Bozinovski… - Pharmacology & …, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

Obesity and cancer: local and systemic mechanisms

NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …

[HTML][HTML] The link between the metabolic syndrome and cancer

S Braun, K Bitton-Worms, D LeRoith - International journal of …, 2011 - ncbi.nlm.nih.gov
Since the incidence of the metabolic syndrome is on the rise in the western world, its
coherence to cancer is becoming more apparent. In this review we discuss the different …